CARBIPHENE HYDROCHLORIDE

CARBIPHENE HYDROCHLORIDE名称

[ CAS 号 ]:
467-22-1

[ 英文名 ]:
CARBIPHENE HYDROCHLORIDE

[英文别名 ]:

CARBIPHENE HYDROCHLORIDE物理化学性质

[ 沸点 ]:
566.3ºC at 760 mmHg

[ 分子式 ]:
C28H35ClN2O2

[ 分子量 ]:
467.04300

[ 闪点 ]:
296.3ºC

[ 精确质量 ]:
466.23900

[ PSA ]:
32.78000

[ LogP ]:
5.40160

[ 蒸汽压 ]:
7.67E-13mmHg at 25°C

CARBIPHENE HYDROCHLORIDE毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AB8400000
CHEMICAL NAME :
Acetamide, 2-ethoxy-N-methyl-N-(2-(methylphenethylamino)ethyl)-2 ,2-diphenyl-, hydrochloride
CAS REGISTRY NUMBER :
467-22-1
LAST UPDATED :
199007
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C28-H34-N2-O2.Cl-H
MOLECULAR WEIGHT :
467.10
WISWESSER LINE NOTATION :
2OXR&R&VN1&2M2R D1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
2 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 6,547,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
370 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 154,484,1965
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
190 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 154,484,1965
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
40 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 154,484,1965
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