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N,N'-二环己基-4-吗啉脒

N,N'-二环己基-4-吗啉脒名称

[ CAS 号 ]:
4975-73-9

[ 中文名 ]:
N,N'-二环己基-4-吗啉脒

[ 英文名 ]:
N,N'-Dicyclohexyl-4-morpholinecarboxamidine

[中文别名 ]:

[英文别名 ]:

4-Morpholinecarboximidamide, N,N'-dicyclohexyl-
N,N'-Dicyclohexyl-4-morpholine carboxamidine
4-(N,N'-Dicyclohexylcarbamimidoyl)morpholine
N,N'-Dicyclohexyl-4-morpholinecarboxamidine
4-(N,N'-Dicyclohexylamidino)morpholine
N,N-Dicyclohexyl-4-Morpholinecarboxamidine
MFCD00063252
N,N'-Dicyclohexyl-4-morpholinecarboximidamide
N,N'-Dicyclohexylmorpholine-4-carboximidamide
EINECS 225-622-1

N,N'-二环己基-4-吗啉脒物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
423.2±55.0 °C at 760 mmHg

[ 熔点 ]:
105-107 °C(lit.)

[ 分子式 ]:
C₁₇H₃₁N₃O

[ 分子量 ]:
293.448

[ 闪点 ]:
209.7±31.5 °C

[ 精确质量 ]:
293.246704

[ PSA ]:
36.86000

[ LogP ]:
2.99

[ 外观性状 ]:
白色晶体结晶粉末

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.600

[ 储存条件 ]:
室温

[ 水溶解性 ]:
可溶于：甲醇

N,N'-二环己基-4-吗啉脒MSDS

详细MSDS(安全技术说明书)

N,N'-二环己基-4-吗啉脒毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LQ4566500

CHEMICAL NAME :: Formamidine, N,N'-dicyclohexyl-1-morpholino-

CAS REGISTRY NUMBER :: 4975-73-9

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C17-H31-N3-O

MOLECULAR WEIGHT :: 293.51

WISWESSER LINE NOTATION :: T6N DOTJ AYUN- AL6TJ&M- AL6TJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 20 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#07096

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N,N'-二环己基-4-吗啉脒安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
26

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
LQ4566500

[ 海关编码 ]:
2934999090

N,N'-二环己基-4-吗啉脒上下游产品

N,N'-二环己基-4-吗啉脒上游产品

N,N'-二环己基-4-吗啉脒下游产品

N,N'-二环己基-4-吗啉脒海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

N,N'-二环己基-4-吗啉脒文献

Enhanced inhibition of orthopoxvirus replication in vitro by alkoxyalkyl esters of cidofovir and cyclic cidofovir.

Antimicrob. Agents Chemother. 46(4) , 991-5, (2002)

The nucleotide phosphonates cidofovir (CDV) and cyclic cidofovir (cCDV) are potent antiviral compounds when administered parenterally but are not well absorbed orally. These compounds have been report...

Synthesis and diuretic activity of alkyl- and arylguanidine analogs of N,N'-dicyclohexyl-4-morpholinecarboxamidine in rats and dogs.

J. Med. Chem. 37(22) , 3693-700, (1994)

Random screening identified N,N'-dicyclohexyl-4-morpholinecarboxamidine (U-18177, 1) as an orally effective nonkaliuretic diuretic in rats. The diuretic profile of 1 and its 1-adamantyl analog (U-3788...

An ATP-sensitive potassium channel blocker suppresses sodium-induced hypertension through increased secretion of urinary kallikrein.

Hypertens. Res. 32(3) , 220-6, (2009)

It is suggested that an ATP-sensitive potassium channel blocker suppresses sodium-induced hypertension through increased secretion of urinary kallikrein. We reported that glibenclamide, an ATP-sensiti...

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