丙利酸钾

丙利酸钾名称

[ CAS 号 ]:
49847-97-4

[ 中文名 ]:
丙利酸钾

[ 英文名 ]:
prorenoate potassium

[英文别名 ]:

丙利酸钾物理化学性质

[ 沸点 ]:
560.4ºC at 760 mmHg

[ 分子式 ]:
C23H31KO4

[ 分子量 ]:
410.58800

[ 闪点 ]:
306.8ºC

[ 精确质量 ]:
410.18600

[ PSA ]:
77.43000

[ LogP ]:
2.63540

丙利酸钾毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GZ2223000
CHEMICAL NAME :
3'H-Cyclopropa(6,7)pregna-4,6-diene-21-carboxylic acid, 6,7-dihydro-17-hydroxy-3-oxo-, monopotassium salt, (6-alpha,7-alpha,17-alpha)-
CAS REGISTRY NUMBER :
49847-97-4
LAST UPDATED :
199506
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C23-H31-O4.K
MOLECULAR WEIGHT :
410.64

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1397 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TOPADD Toxicologic Pathology. (c/o Dr. F.A. de la Iglesia, Warner-Lambert Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 1978- Volume(issue)/page/year: 13,315,1985 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
9100 mg/kg/13W-I
TOXIC EFFECTS :
Liver - changes in liver weight Endocrine - changes in thyroid weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)
REFERENCE :
TOPADD Toxicologic Pathology. (c/o Dr. F.A. de la Iglesia, Warner-Lambert Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 1978- Volume(issue)/page/year: 13,315,1985
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