丙利酸钾
丙利酸钾名称
[ CAS 号 ]:
49847-97-4
[ 中文名 ]:
丙利酸钾
[ 英文名 ]:
prorenoate potassium
[英文别名 ]:
- Prorenoato potasico
- Potassium prorenoate
丙利酸钾物理化学性质
[ 沸点 ]:
560.4ºC at 760 mmHg
[ 分子式 ]:
C23H31KO4
[ 分子量 ]:
410.58800
[ 闪点 ]:
306.8ºC
[ 精确质量 ]:
410.18600
[ PSA ]:
77.43000
[ LogP ]:
2.63540
丙利酸钾毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GZ2223000
- CHEMICAL NAME :
- 3'H-Cyclopropa(6,7)pregna-4,6-diene-21-carboxylic acid, 6,7-dihydro-17-hydroxy-3-oxo-, monopotassium salt, (6-alpha,7-alpha,17-alpha)-
- CAS REGISTRY NUMBER :
- 49847-97-4
- LAST UPDATED :
- 199506
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C23-H31-O4.K
- MOLECULAR WEIGHT :
- 410.64
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1397 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TOPADD Toxicologic Pathology. (c/o Dr. F.A. de la Iglesia, Warner-Lambert Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 1978- Volume(issue)/page/year: 13,315,1985 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 9100 mg/kg/13W-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Endocrine - changes in thyroid weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)
- REFERENCE :
- TOPADD Toxicologic Pathology. (c/o Dr. F.A. de la Iglesia, Warner-Lambert Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 1978- Volume(issue)/page/year: 13,315,1985
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