丙美卡因
丙美卡因名称
[ CAS 号 ]:
499-67-2
[ 中文名 ]:
丙美卡因
[ 英文名 ]:
proxymetacaine
[英文别名 ]:
- 2-(diethylamino)ethyl 3-amino-4-propoxybenzoate
丙美卡因物理化学性质
[ 密度 ]:
1.065 g/cm3
[ 沸点 ]:
434.4ºC at 760 mmHg
[ 熔点 ]:
182-183.30C
[ 分子式 ]:
C16H26N2O3
[ 分子量 ]:
294.38900
[ 闪点 ]:
216.5ºC
[ 精确质量 ]:
294.19400
[ PSA ]:
64.79000
[ LogP ]:
3.13740
[ 蒸汽压 ]:
9.5E-08mmHg at 25°C
[ 折射率 ]:
1.527
[ 储存条件 ]:
Refrigerator
丙美卡因毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DG3058000
- CHEMICAL NAME :
- Benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester
- CAS REGISTRY NUMBER :
- 499-67-2
- BEILSTEIN REFERENCE NO. :
- 2745891
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C16-H26-N2-O3
- MOLECULAR WEIGHT :
- 294.44
- WISWESSER LINE NOTATION :
- 3OR BZ DVO2N2&2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4800 ug/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 63,369,1938 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M0782 No. of Facilities: 5 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 14 (estimated)
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