3-Methoxy-4,5α-epoxy-7,8-didehydro-17-methylmorphinan

名称

[ CAS 号 ]:
5121-66-4

[ 英文名 ]:
3-Methoxy-4,5α-epoxy-7,8-didehydro-17-methylmorphinan

[英文别名 ]:

物理化学性质

[ 密度 ]:
1.26g/cm3

[ 沸点 ]:
411.6ºC at 760 mmHg

[ 分子式 ]:
C₁₈H₂₁NO₂

[ 分子量 ]:
283.36500

[ 闪点 ]:
149.8ºC

[ 精确质量 ]:
283.15700

[ PSA ]:
21.70000

[ LogP ]:
2.46820

[ 折射率 ]:
1.644

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QC7665000

CHEMICAL NAME :: Morphinan, 7,8-didehydro-4,5-alpha-epoxy-3-methoxy-17-methyl-

CAS REGISTRY NUMBER :: 5121-66-4

LAST UPDATED :: 199712

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C18-H21-N-O2

MOLECULAR WEIGHT :: 283.40

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 60 mg/kg

TOXIC EFFECTS :: Behavioral - rigidity (including catalepsy) Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 16,174,1964

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