L-半胱氨酸盐酸盐(无水物)

L-Cysteine hydrochloride 是一种条件必需氨基酸,是硫化氢 (H2S)、谷胱甘肽和牛磺酸等生物活性分子的前体。L-Cysteine hydrochloride 能抑制胃饥饿素,降低啮齿动物和人类的食欲。

[ 描述 ]:

[ 相关类别 ]:

[参考文献]

[ 沸点 ]:
293.9ºC at 760 mmHg

[ 熔点 ]:
140-142ºC

[ 分子式 ]:
C₃H₈ClNO₂S

[ 分子量 ]:
157.619

[ 闪点 ]:
131.5ºC

[ 精确质量 ]:
156.996429

[ PSA ]:
102.12000

[ LogP ]:
0.83040

[ 外观性状 ]:
白色固体

[ 储存条件 ]:
室温

详细MSDS(安全技术说明书)

CHEMICAL IDENTIFICATION

RTECS NUMBER :

HA2275000

CHEMICAL NAME :

Cysteine, hydrochloride, L-

CAS REGISTRY NUMBER :

52-89-1

LAST UPDATED :

199710

DATA ITEMS CITED :

10

MOLECULAR FORMULA :

C3-H7-N-O2-S.Cl-H

MOLECULAR WEIGHT :

157.63

WISWESSER LINE NOTATION :

SH1YZVQ &GH -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

1250 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

771 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Unreported

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

3 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :

Cytogenetic analysis

TEST SYSTEM :

Rodent - hamster Fibroblast

DOSE/DURATION :

2 gm/L

REFERENCE :

FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 22,623,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81863 No. of Facilities: 114 (estimated) No. of Industries: 3 No. of Occupations: 9 No. of Employees: 6426 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81863 No. of Facilities: 492 (estimated) No. of Industries: 2 No. of Occupations: 7 No. of Employees: 7343 (estimated) No. of Female Employees: 5313 (estimated)

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
HA2275000

[ 海关编码 ]:
2930909090

详细合成路线

L-半胱氨酸盐酸盐(无水物)上游产品

L-半胱氨酸盐酸盐(无水物)下游产品

1.将胱氨酸溶于稀盐酸中，过滤加入锡粒升温回流。将还原液用水稀释，移去剩余锡粒，通过硫化氢使饱和，过滤，滤渣用少量水洗，将洗液、滤液合并，减压浓缩，冷却结晶，干燥得盐酸L-半胱氨酸。

2. 由毛发中所含的α -角蛋白水解可得胱氨酸，再经化学还原或电解还原成半胱氨酸，再加盐酸成盐。

[ 海关编码 ]: 2930909090

[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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