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2-氨基-4-噻唑乙酸乙酯

2-氨基-4-噻唑乙酸乙酯用途

【用途一】
用作头孢类药物中间体

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2-氨基-4-噻唑乙酸乙酯名称

[ CAS 号 ]:
53266-94-7

[ 中文名 ]:
2-氨基-4-噻唑乙酸乙酯

[ 英文名 ]:
Ethyl (2-amino-1,3-thiazol-4-yl)acetate

[中文别名 ]:

[英文别名 ]:

Ethyl 2-(2-aminothiazol-4-yl)acetate
MFCD00005330
Ethyl (2-amino-1,3-thiazol-4-yl)acetate
(2-Amino-4-thiazolyl)acetic Acid Ethyl Ester
Ethyl-2-(2-amino-4-thiazole-4-yl) acetate
EINECS 258-452-1
4-Thiazoleacetic acid, 2-amino-, ethyl ester
Ethyl (2-AMino-4-thiazolyl)acetate
Ethyl 2-Amino-4-Thiazoleacetate
ethyl 2-(2-amino-1,3-thiazol-4-yl)acetate

2-氨基-4-噻唑乙酸乙酯物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
318.5±17.0 °C at 760 mmHg

[ 熔点 ]:
92-94 °C(lit.)

[ 分子式 ]:
C₇H₁₀N₂O₂S

[ 分子量 ]:
186.232

[ 闪点 ]:
146.4±20.9 °C

[ 精确质量 ]:
186.046295

[ PSA ]:
93.45000

[ LogP ]:
0.66

[ 外观性状 ]:
黄色粉末

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.576

[ 储存条件 ]:
室温，干燥

[ 水溶解性 ]:
可溶于：甲醇

2-氨基-4-噻唑乙酸乙酯MSDS

2-氨基-4-噻唑乙酸乙酯安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S37/39-S26

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2934100090

2-氨基-4-噻唑乙酸乙酯合成路线

2-氨基-4-噻唑乙酸乙酯上下游产品

2-氨基-4-噻唑乙酸乙酯上游产品

2-氨基-4-噻唑乙酸乙酯下游产品

2-氨基-4-噻唑乙酸乙酯海关

[ 海关编码 ]: 2934100090

[ 中文概述 ]:
2934100090. 结构上含有一个非稠合噻唑环的化合物(不论是否氢化). 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

2-氨基-4-噻唑乙酸乙酯文献

Dichloridobis[ethyl 2-(2-amino-1,3-thia-zol-4-yl)acetate-κ(2)O,N(3)]cadmium.

Acta Crystallogr. Sect. E Struct. Rep. Online 68(6) , m788-m789, (2012)

The asymmetric unit of the title compound, [CdCl(2)(C(7)H(10)N(2)O(2)S)(2)], contains two complex molecules with similar configurations. The Cd(II) atoms are each six-coordinated by two thiazole N and...

Bis(2-amino-thia-zole-4-acetato)aquazinc(II).

Acta Crystallogr. Sect. E Struct. Rep. Online 65(12) , m1517-m1517, (2009)

In the title compound, [Zn(C(5)H(5)N(2)O(2)S)(2)(H(2)O)], the central Zn atom (2 site symmetry) is five-coordinated by two N and three O atoms [Zn-N = 2.047 (3) Å, Zn-O = 2.099 (2) and 1.974 (4) Å] in...

Discovery of 3-(4-methanesulfonylphenoxy)-N-[1-(2-methoxy-ethoxymethyl)-1H-pyrazol-3-yl]-5-(3-methylpyridin-2-yl)-benzamide as a novel glucokinase activator (GKA) for the treatment of type 2 diabetes mellitus

Bioorg. Med. Chem. 22(7) , 2280-93, (2014)

Novel heteroaryl-containing benzamide derivatives were synthesized and screened using an in vitro assay measuring increases in glucose uptake and glucokinase activity stimulated by 10mM glucose in rat...

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