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12(S)-HETE

12(S)-HETE名称

[ CAS 号 ]:
54397-83-0

[ 中文名 ]:
12(S)-HYDROXY-(5Z,8Z,10E,14Z)-EICOSATETRAENOIC ACID

[ 英文名 ]:
12S-HETE

[英文别名 ]:

MFCD00036916
12-HETE
12(S)-HETE

12(S)-HETE物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
487.7±45.0 °C at 760 mmHg

[ 分子式 ]:
C₂₀H₃₂O₃

[ 分子量 ]:
320.466

[ 闪点 ]:
262.8±25.2 °C

[ 精确质量 ]:
320.235138

[ PSA ]:
57.53000

[ LogP ]:
5.45

[ 外观性状 ]:
液体

[ 蒸汽压 ]:
0.0±2.8 mmHg at 25°C

[ 折射率 ]:
1.514

[ 储存条件 ]:
-20℃

12(S)-HETEMSDS

详细MSDS(安全技术说明书)

12(S)-HETE安全信息

[ 符号 ]:

GHS02, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H319

[ 警示性声明 ]:
P210-P280-P305 + P351 + P338-P337 + P313-P403 + P235

[ 危害码 (欧洲) ]:
F,Xi

[ 风险声明 (欧洲) ]:
R11

[ 安全声明 (欧洲) ]:
S7-S16-S26-S36

[ 危险品运输编码 ]:
UN 1170 3/PG 2

[ 海关编码 ]:
2918199090

12(S)-HETE上下游产品

12(S)-HETE上游产品

12(S)-HETE下游产品

12(S)-HETE海关

[ 海关编码 ]: 2918199090

[ 中文概述 ]:
HS: 2918199090. 其他含醇基但不含其他含氧基羧酸（包括其酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

12(S)-HETE文献

Lack of association of ALOX12 and ALOX15B polymorphisms with psoriasis despite altered urinary excretion of 12(S)-hydroxyeicosatetraenoic acid.

Br. J. Dermatol. 172(2) , 337-44, (2015)

Pro- and anti-inflammatory metabolites of arachidonic acid - eicosanoids - participate in skin homeostasis, affecting the growth and differentiation of keratinocytes. Alterations of 12-lipoxygenase (L...

Identification of 12/15-lipoxygenase as a regulator of axon degeneration through high-content screening.

J. Neurosci. 35(7) , 2927-41, (2015)

Axon degeneration is a programed process that takes place during development, in response to neuronal injury, and as a component of neurodegenerative disease pathology, yet the molecular mechanisms th...

MyD88-BLT2-dependent cascade contributes to LPS-induced interleukin-6 production in mouse macrophage.

Exp. Mol. Med. 47 , e156, (2015)

Endotoxic responses to bacterial lipopolysaccharide (LPS) are triggered by Toll-like receptor 4 (TLR4) and involve the production of inflammatory mediators, including interleukin-6 (IL-6), by macropha...

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