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H-Leu-CMK.HCl

H-Leu-CMK.HCl用途

(S) -3-氨基-1-氯-5-甲基己烷-2-酮盐酸盐是亮氨酸衍生物[1]。

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H-Leu-CMK.HCl名称

[ CAS 号 ]:
54518-92-2

[ 中文名 ]:
L-亮氨酸氯甲基酮盐酸盐

[ 英文名 ]:
H-Leu-CMK.HCl

[英文别名 ]:

l-leucine chloromethyl ketone hydrochloride
MFCD00238011

H-Leu-CMK.HCl生物活性

[ 描述 ]:

(S) -3-氨基-1-氯-5-甲基己烷-2-酮盐酸盐是亮氨酸衍生物[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

氨基酸和氨基酸衍生物已被商业化用作能量补充剂。它们影响合成代谢激素的分泌、运动期间的燃料供应、压力相关任务期间的精神表现,并防止运动引起的肌肉损伤。它们被认为是有益的能生膳食物质[1]。

[参考文献]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

H-Leu-CMK.HCl物理化学性质

[ 分子式 ]:
C₇H₁₅Cl₂NO

[ 分子量 ]:
200.10600

[ 精确质量 ]:
199.05300

[ PSA ]:
43.09000

[ LogP ]:
2.67000

[ 储存条件 ]:
2-8°C，惰性气体

H-Leu-CMK.HClMSDS

H-Leu-CMK.HCl安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3.0

[ 海关编码 ]:
2922399090

H-Leu-CMK.HCl合成路线

H-Leu-CMK.HCl上下游产品

H-Leu-CMK.HCl上游产品

H-Leu-CMK.HCl下游产品

H-Leu-CMK.HCl海关

[ 海关编码 ]: 2922399090

[ 中文概述 ]:
2922399090 其他氨基醛、氨基酮及其盐（包括氨基醌及其盐，但含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

H-Leu-CMK.HCl文献

Acylpeptide hydrolase: inhibitors and some active site residues of the human enzyme.

J. Biol. Chem. 267 , 3811-3818, (1992)

Acylpeptide hydrolase may be involved in N-terminal deacetylation of nascent polypeptide chains and of bioactive peptides. The activity of this enzyme from human erythrocytes is sensitive to anions su...

Acetylleucine chloromethyl ketone, an inhibitor of acylpeptide hydrolase, induces apoptosis of U937 cells.

Biochem. Biophys. Res. Commun. 263 , 139-142, (1999)

Acetylleucine chloromethyl ketone (ALCK), an inhibitor of acylpeptide hydrolase (ACPH), inhibited the growth of human monoblastic U937 cells in a dose- and time-dependent manner. Morphology of the ALC...

Chloromethyl ketones are insulin-like stimulators of lipid synthesis in locust fat body.

Arch. Insect Biochem. Physiol. 39 , 9-17, (1998)

N alpha-tosyl-L-lysine chloromethyl ketone (TLCK) stimulates lipid synthesis in locust fat body in vitro, and is able to reverse the inhibitory effects of AKH-I on lipid synthesis. Effective stimulato...

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