核酸酶P1 来源于桔青霉菌

核酸酶P1 来源于桔青霉菌用途

核酸酶P1是一种单链特异性内切核酸酶,它将核酸水解为5'-单核苷酸,并切割双链核酸的单链区。核酸酶P1是分子生物学领域中最知名的单链特异性核酸酶之一,广泛应用于制药和食品工业[1]。

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核酸酶P1 来源于桔青霉菌名称

[ CAS 号 ]:
54576-84-0

[ 中文名 ]:
核酸酶P1

[ 英文名 ]:
Nuclease P1

[英文别名 ]:

EINECS 253-443-9
MFCD00131010

核酸酶P1 来源于桔青霉菌生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

[参考文献]

[1]. Mitiushkina NV, et al. Preparation of Duplex Sequencing Libraries for Archival Paraffin-Embedded Tissue Samples Using Single-Strand-Specific Nuclease P1. Int J Mol Sci. 2022 Apr 21;23(9):4586.

核酸酶P1 来源于桔青霉菌物理化学性质

[ 外观性状 ]:
白色冻干粉

[ 储存条件 ]:
2-8°C

核酸酶P1 来源于桔青霉菌安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

核酸酶P1 来源于桔青霉菌文献

Hydroxyl-radical-induced oxidation of 5-methylcytosine in isolated and cellular DNA.

Nucleic Acids Res. 42(11) , 7450-60, (2014)

The methylation and oxidative demethylation of cytosine in CpG dinucleotides plays a critical role in the regulation of genes during cell differentiation, embryogenesis and carcinogenesis. Despite its...

Effect of 8-oxoguanine glycosylase deficiency on aflatoxin B1 tumourigenicity in mice.

Mutagenesis 30 , 401-9, (2015)

The mycotoxin aflatoxin B1 (AFB1) may initiate cancer by causing oxidatively damaged DNA, specifically by causing 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) lesions. Base excision repair removes th...

SAW1 is required for SDSA double-strand break repair in S. cerevisiae.

Biochem. Biophys. Res. Commun. 445(3) , 602-7, (2014)

SAW1, coding for Saw1, is required for single-strand annealing (SSA) DNA double-strand break (DSB) repair in Saccharomycescerevisiae. Saw1 physically associates with Rad1 and Rad52 and recruits the Ra...

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