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12-脱氧佛13-苯乙酸20-醋酸

12-脱氧佛13-苯乙酸20-醋酸名称

[ CAS 号 ]:
54662-30-5

[ 中文名 ]:
12-脱氧佛13-苯乙酸20-醋酸

[ 英文名 ]:
12-deoxyphorbol 13-phenylacetate 20-acetate

[英文别名 ]:

12-deoxyphorbolphenylacetate-20-acetate
3-acetate9a-phenylacetate
12-DPPAA

12-脱氧佛13-苯乙酸20-醋酸物理化学性质

[ 密度 ]:
1.29g/cm3

[ 沸点 ]:
635.7ºC at 760 mmHg

[ 分子式 ]:
C₃₀H₃₆O₇

[ 分子量 ]:
508.60300

[ 闪点 ]:
204.3ºC

[ 精确质量 ]:
508.24600

[ PSA ]:
110.13000

[ LogP ]:
3.32370

[ 折射率 ]:
1.607

12-脱氧佛13-苯乙酸20-醋酸安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H300-H310-H315-H319-H330-H335

[ 警示性声明 ]:
P260-P264-P280-P284-P301 + P310-P302 + P350

[ 危险品运输编码 ]:
UN 2811 6.1 / PGIII

12-脱氧佛13-苯乙酸20-醋酸文献

Phosphorylation of connexin43 and inhibition of gap junctional communication in 12-O-tetradecanoylphorbol-13-acetate-exposed R6 fibroblasts: minor role of protein kinase C beta I and mu.

Carcinogenesis 22(2) , 221-31, (2001)

12-O:-tetradecanoylphorbol-13-acetate (TPA) inhibits gap junctional communication in many cell culture systems, but TPA-induced phosphorylation of the gap junction protein connexin43 (Cx43) varies muc...

Protein kinase C modulates insulin action in human skeletal muscle.

Am. J. Physiol. Endocrinol. Metab. 278(3) , E553-62, (2000)

There is good evidence from cell lines and rodents that elevated protein kinase C (PKC) overexpression/activity causes insulin resistance. Therefore, the present study determined the effects of PKC ac...

Rapid loss of blood-brain barrier P-glycoprotein activity through transporter internalization demonstrated using a novel in situ proteolysis protection assay.

J. Cereb. Blood Flow Metab. 30(9) , 1593-7, (2010)

Blood-brain barrier (BBB) P-glycoprotein activity is rapidly reduced by vascular endothelial growth factor (VEGF) acting via Src and by tumor necrosis factor-alpha acting via protein kinase C (PKC)bet...

更多文献

12-脱氧佛13-苯乙酸20-醋酸

12-脱氧佛13-苯乙酸20-醋酸名称

12-脱氧佛13-苯乙酸20-醋酸物理化学性质

12-脱氧佛13-苯乙酸20-醋酸安全信息

12-脱氧佛13-苯乙酸20-醋酸文献

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