尖刺檗鹼
尖刺檗鹼名称
[ CAS 号 ]:
548-40-3
[ 中文名 ]:
尖刺檗鹼
[ 英文名 ]:
2H-1,24:12,15-Dietheno-6,10-metheno-16H-pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinolin-9-ol,3,4,4a,5,16a,17,18,19-octahydro-21,22,26-trimethoxy-4,17-dimethyl-, (4aR,16aS)-
[英文别名 ]:
- Oxyacanthine
- Oxyacanthin
- vinetine
- 6,7,6'-trimethoxy-2,2'-dimethyl-oxyacanthan-12'-ol
- 6,6',7-Trimethoxy-2,2'-dimethyloxyacanthan-12'-ol
- Oxycanthine
尖刺檗鹼物理化学性质
[ 密度 ]:
1.204g/cm3
[ 沸点 ]:
707ºC at 760mmHg
[ 分子式 ]:
C37H40N2O6
[ 分子量 ]:
608.72300
[ 闪点 ]:
381.4ºC
[ 精确质量 ]:
608.28900
[ PSA ]:
72.86000
[ LogP ]:
6.73520
[ 折射率 ]:
1.601
尖刺檗鹼毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RR6475000
- CHEMICAL NAME :
- Oxyacanthan-12'-ol, 6,6',7-trimethoxy-2,2'-dimethyl-
- CAS REGISTRY NUMBER :
- 548-40-3
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C37-H40-N2-O6
- MOLECULAR WEIGHT :
- 608.79
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,17,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 24,2413,1976
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