9H-Fluorene-9-carboxylicacid, 2-(diethylamino)ethyl ester, hydrochloride (1:1)

名称

[ CAS 号 ]:
548-65-2

[ 英文名 ]:
9H-Fluorene-9-carboxylicacid, 2-(diethylamino)ethyl ester, hydrochloride (1:1)

[英文别名 ]:

Robitrin
Pavatrine hydrochloride
Ro 2-3208
Pavatrine
Fluorene-9-carboxylic acid,3-quinuclidinyl ester
Spasmadrina

物理化学性质

[ 沸点 ]:
447ºC at 760mmHg

[ 分子式 ]:
C₂₀H₂₄ClNO₂

[ 分子量 ]:
345.86300

[ 闪点 ]:
149.7ºC

[ 精确质量 ]:
345.15000

[ PSA ]:
29.54000

[ LogP ]:
4.48590

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LL6220000

CHEMICAL NAME :: Fluorene-9-carboxylic acid, 2-(diethylamino)ethyl ester, hydrochloride

CAS REGISTRY NUMBER :: 548-65-2

LAST UPDATED :: 199709

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C20-H23-N-O2.Cl-H

MOLECULAR WEIGHT :: 345.90

WISWESSER LINE NOTATION :: L B656 HHJ HVO2N2&2 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,274,1942

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 15 mg/kg

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Behavioral - excitement

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 46,58,1957

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安全信息

[ 海关编码 ]:
2922199090

合成路线

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海关

[ 海关编码 ]: 2922199090

[ 中文概述 ]:
2922199090. 其他氨基醇及其醚，酯和它们的盐（但含一种以上含氧基的除外）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%