西酞普兰USP相关物质F
西酞普兰USP相关物质F名称
[ CAS 号 ]:
55011-89-7
[ 中文名 ]:
西酞普兰USP相关物质F
[ 英文名 ]:
2-(3,3-diphenylpropyl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine
[英文别名 ]:
西酞普兰USP相关物质F物理化学性质
[ 分子式 ]:
C23H30N2
[ 分子量 ]:
334.49800
[ 精确质量 ]:
334.24100
[ PSA ]:
6.48000
[ LogP ]:
4.25450
西酞普兰USP相关物质F安全信息
[ 符号 ]:
GHS06
[ 信号词 ]:
Danger
[ 危害声明 ]:
H301
[ 警示性声明 ]:
P301 + P310
[ 危害码 (欧洲) ]:
T
[ 风险声明 (欧洲) ]:
25
[ 安全声明 (欧洲) ]:
45
[ 危险品运输编码 ]:
UN 2811 6.1 / PGIII
西酞普兰USP相关物质F文献
Eur. J. Clin. Pharmacol. 19(3) , 217-23, (1981)
The pharmacokinetic constants and rectal bioavailability of the narcotic analgesic ketobemidone were determined in six male patients after surgery. Plasma concentrations were measured following intrav...
The mu1 and mu2 opioid receptor binding of ketobemidone, norketobemidone and 3-dimethylamino-1,1-diphenylbutene.Pharmacol. Toxicol. 79(2) , 103-4, (1996)
Ketobemidone plus (RS)-3-dimethylamino-1,1-diphenylbut-1-ene (A29) is more potent at NMDA receptors than ketobemidone alone: evidence for A29 as a non-competitive NMDA receptor antagonist.
Pharmacol. Toxicol. 82(3) , 157-60, (1998)
The opioid, ketobemidone, has previously been shown to be a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist. In Denmark, ketobemidone is available in a formulation which contains ketob...
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