盐酸布替林

盐酸布替林名称

[ CAS 号 ]:
5585-73-9

[ 中文名 ]:
盐酸布替林

[ 英文名 ]:
Butriptyline hydrochloride

[中文别名 ]:

盐酸乙丁替林

[英文别名 ]:

ButriptylineHCl
Evadyne
Butriptylene hydrochloride
Butriptylin*HCl

盐酸布替林物理化学性质

[ 密度 ]:
0.994g/cm3

[ 沸点 ]:
387.7ºC at 760 mmHg

[ 熔点 ]:
188-190ºC

[ 分子式 ]:
C₂₁H₂₈ClN

[ 分子量 ]:
329.90700

[ 闪点 ]:
168.8ºC

[ 精确质量 ]:
329.19100

[ PSA ]:
3.24000

[ LogP ]:
5.30690

[ 折射率 ]:
1.554

[ 储存条件 ]:
库房通风低温干燥,与食品原料类分开存放

盐酸布替林毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HP0350000

CHEMICAL NAME :: 5H-Dibenzo(a,d)cycloheptene-5-propylamine, 10,11-dihydro-N,N,beta-trimethyl-, hydrochloride, DL-

CAS REGISTRY NUMBER :: 5585-73-9

LAST UPDATED :: 199012

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C21-H27-N.Cl-H

MOLECULAR WEIGHT :: 329.95

WISWESSER LINE NOTATION :: L C676&T&J B1Y1&1N1&1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,62,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,62,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 345 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,62,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 120 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,62,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 48 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,62,1972

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盐酸布替林安全信息

[ 危险品运输编码 ]:
UN 3249

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)