碘丙甘油
碘丙甘油名称
[ CAS 号 ]:
5634-39-9
[ 中文名 ]:
碘丙甘油
[ 英文名 ]:
2-(1-iodoethyl)-1,3-dioxolan-4-ylmethanol
[中文别名 ]:
[英文别名 ]:
- Iodopropylidene glycerol
- 2-(1-Iodoethyl)-1,3-dioxolan-4-ylmethanol
- Glycerol,Iodinated
- Organidin
- Iodinated glycerol
- 1,3-Dioxolane-4-methanol,2-(1-iodoethyl)
碘丙甘油物理化学性质
[ 密度 ]:
1.794g/cm3
[ 沸点 ]:
294.9ºC at 760 mmHg
[ 分子式 ]:
C6H11IO3
[ 分子量 ]:
258.05400
[ 闪点 ]:
132.1ºC
[ 精确质量 ]:
257.97500
[ PSA ]:
38.69000
[ LogP ]:
0.54370
[ 折射率 ]:
1.545
碘丙甘油毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- JI1800000
- CHEMICAL NAME :
- 1,3-Dioxolane-4-methanol, 2-(1-iodoethyl)-
- CAS REGISTRY NUMBER :
- 5634-39-9
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 14
- MOLECULAR FORMULA :
- C6-H11-I-O3
- MOLECULAR WEIGHT :
- 258.07
- WISWESSER LINE NOTATION :
- T5O COTJ BYI1 D1Q &T5O COTJ B2I D1Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6 gm/kg/16D-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 32500 mg/kg/13W-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 32500 mg/kg/13W-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 64375 mg/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Endocrine - thyroid tumors Blood - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 64375 mg/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Endocrine - tumors
- TYPE OF TEST :
- Sister chromatid exchange
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 167 mg/L
- REFERENCE :
- NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-340,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81848 No. of Facilities: 864 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 1099 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81848 No. of Facilities: 85 (estimated) No. of Industries: 2 No. of Occupations: 6 No. of Employees: 854 (estimated) No. of Female Employees: 265 (estimated)
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