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路易斯A三糖

路易斯A三糖用途

刘易斯a三糖(Lewis a)是一种存在于精子多糖结构中的三糖。Lewis a三糖也是HL-60细胞表面聚糖结构的主要成分[1]。

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路易斯A三糖名称

[ CAS 号 ]:
56570-03-7

[ 中文名 ]:
路易斯A 三糖

[ 英文名 ]:
Lewis-a trisaccharide

[英文别名 ]:

lewis a trisaccharide

路易斯A三糖生物活性

[ 描述 ]:

刘易斯a三糖(Lewis a)是一种存在于精子多糖结构中的三糖。Lewis a三糖也是HL-60细胞表面聚糖结构的主要成分[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. A C Fitchette-Lainé, et al. N-glycans harboring the Lewis a epitope are expressed at the surface of plant cells. Plant J. 1997 Dec;12(6):1411-7.

路易斯A三糖物理化学性质

[ 密度 ]:
1.6g/cm3

[ 沸点 ]:
977.2ºC at 760mmHg

[ 熔点 ]:
160-162ºC

[ 分子式 ]:
C₂₀H₃₅NO₁₅

[ 分子量 ]:
529.49000

[ 闪点 ]:
544.8ºC

[ 精确质量 ]:
529.20100

[ PSA ]:
257.32000

[ 外观性状 ]:
白色粉末

[ 折射率 ]:
1.632

[ 储存条件 ]:
2-8°C

路易斯A三糖安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

路易斯A三糖文献

N-glycans harboring the Lewis a epitope are expressed at the surface of plant cells.

Plant J. 12(6) , 1411-7, (1997)

In plants, N-linked glycans are processed in the Golgi apparatus to complex-type N-glycans of limited size containing a beta(1,2)-xylose and/or an alpha(1,3)-fucose residue. Larger mono- and bi-antenn...

Studies on the three-dimensional behaviour of the selectin ligands Lewis(a) and sulphated Lewis(a) using NMR spectroscopy and molecular dynamics simulations.

Glycobiology 4(1) , 49-57, (1994)

Sulphated blood group Lewis(a)/Lewis(x) (Le(a)/Le(x)) type sequences, with sulphate at the 3-position of galactose, have emerged as potent ligands for the endothelial adhesion molecule E-selectin and ...

CA-S27: a novel Lewis a associated carbohydrate epitope is diagnostic and prognostic for cholangiocarcinoma.

Cancer Sci. 104 , 1278-1284, (2013)

Early and specific diagnosis is critical for treatment of cholangiocarcinoma (CCA). In this study, a carbohydrate antigen-S27 (CA-S27) monoclonal antibody (mAb) was established using pooled CCA tissue...

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