盐酸乙哌立松
盐酸乙哌立松用途
盐酸乙哌立松名称
[ CAS 号 ]:
56839-43-1
[ 中文名 ]:
盐酸乙哌立松
[ 英文名 ]:
Eperisone hydrochloride
[中文别名 ]:
[英文别名 ]:
- MFCD00941459
盐酸乙哌立松生物活性
[ 描述 ]:
[ 相关类别 ]:
[参考文献]
盐酸乙哌立松物理化学性质
[ 密度 ]:
0.994g/cm3
[ 沸点 ]:
386.8ºC at 760mmHg
[ 熔点 ]:
168-174ºC
[ 分子式 ]:
C17H26ClNO
[ 分子量 ]:
295.84700
[ 闪点 ]:
137.4ºC
[ 精确质量 ]:
295.17000
[ PSA ]:
20.31000
[ LogP ]:
4.29360
[ 外观性状 ]:
白色或类似至白色结晶粉末带有特有的气味和苦味道
[ 储存条件 ]:
-20°C Freezer
盐酸乙哌立松MSDS
盐酸乙哌立松毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UH1755000
- CHEMICAL NAME :
- Propiophenone, 4'-ethyl-2-methyl-3-piperidino-, hydrochloride
- CAS REGISTRY NUMBER :
- 56839-43-1
- LAST UPDATED :
- 199703
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C17-H25-N-O.Cl-H
- MOLECULAR WEIGHT :
- 295.89
- WISWESSER LINE NOTATION :
- T6NTJ A1Y1&VR D2 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1002 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Autonomic Nervous System - smooth muscle relaxant (mechanism undefined, spasmolytic) Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 19,1743,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 490 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 21,939,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 51 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 21,939,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 21,939,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 324 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 107,705,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 256 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 21,939,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 43 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 21,939,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 280 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 21,939,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- >750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,204,1990 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 18200 mg/kg/13W-C
- TOXIC EFFECTS :
- Liver - changes in liver weight Kidney, Ureter, Bladder - other changes in urine composition Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 21,939,1981
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 22313 mg/kg/1Y-I
- TOXIC EFFECTS :
- Blood - normocytic anemia Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases Related to Chronic Data - death
- REFERENCE :
- KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 16,7156,1982
盐酸乙哌立松合成路线
盐酸乙哌立松上下游产品
盐酸乙哌立松上游产品
盐酸乙哌立松下游产品
相关药品:
推荐生产厂家/供应商:
公司名:上海化源世纪贸易有限公司
区域:上海市普陀区
价格:
联系人:徐乾明
产品详情:1-(4-乙基苯基)-2-甲基-3-(哌啶-1-基)丙-1-酮盐酸盐
公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
价格:
¥1026.9/100mg
¥30.9/1g
¥1535.9/2g
¥779.9/100g
联系人:阿拉丁
产品详情:盐酸哌立松
公司名:上海创赛科技有限公司
区域:上海市嘉定区
价格:
¥392.0/5mg
联系人:夏言
产品详情:[Perfemiker]Eperisone hydrochloride,97%
公司名:湖北魏氏化学试剂股份有限公司
区域:武汉市洪山区
价格:
¥需询单/5mg
¥需询单/25mg
¥需询单/10g
¥需询单/50g
联系人:张栋
产品详情:盐酸乙哌立松
查看所有供应商请点击:
相关化合物
【盐酸乙哌立松】化源网提供盐酸乙哌立松CAS号56839-43-1,盐酸乙哌立松MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询盐酸乙哌立松上化源网,专业又轻松。>>电脑版:盐酸乙哌立松
标题:盐酸乙哌立松_MSDS_用途_密度_盐酸乙哌立松CAS号【56839-43-1】_化源网 地址:https://m.chemsrc.com/mip/cas/56839-43-1_819112.html