1,4-bis(chloromethoxymethyl)benzene

1,4-bis(chloromethoxymethyl)benzene名称

[ CAS 号 ]:
56894-91-8

[ 英文名 ]:
1,4-bis(chloromethoxymethyl)benzene

1,4-bis(chloromethoxymethyl)benzene物理化学性质

[ 密度 ]:
1.233g/cm3

[ 沸点 ]:
307.1ºC at 760 mmHg

[ 分子式 ]:
C₁₀H₁₂Cl₂O₂

[ 分子量 ]:
235.10700

[ 闪点 ]:
114.4ºC

[ 精确质量 ]:
234.02100

[ PSA ]:
18.46000

[ LogP ]:
3.11240

[ 折射率 ]:
1.526

[ 储存条件 ]:
库房通风低温干燥

1,4-bis(chloromethoxymethyl)benzene毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CY8420000

CHEMICAL NAME :: Benzene, 1,4-bis(chloromethoxymethyl)-

CAS REGISTRY NUMBER :: 56894-91-8

LAST UPDATED :: 199510

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C10-H12-Cl2-O2

MOLECULAR WEIGHT :: 235.12

WISWESSER LINE NOTATION :: G1O1R D1O1G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2590 mg/kg/72W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2553,1975

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 310 mg/kg/78W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2553,1975

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 970 mg/kg/81W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2553,1975 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,37,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,37,1977 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

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