6-TRIFLUOROMETHYLCYCLOPHOSPHAMIDE
6-TRIFLUOROMETHYLCYCLOPHOSPHAMIDE名称
[ CAS 号 ]:
57165-71-6
[ 英文名 ]:
6-TRIFLUOROMETHYLCYCLOPHOSPHAMIDE
[英文别名 ]:
- 6-Trifluoromethylcyclophosphamide
6-TRIFLUOROMETHYLCYCLOPHOSPHAMIDE物理化学性质
[ 密度 ]:
1.44g/cm3
[ 沸点 ]:
336.3ºC at 760 mmHg
[ 分子式 ]:
C8H14Cl2F3N2O2P
[ 分子量 ]:
329.08400
[ 闪点 ]:
157.2ºC
[ 精确质量 ]:
328.01200
[ PSA ]:
51.38000
[ LogP ]:
3.14370
[ 折射率 ]:
1.464
6-TRIFLUOROMETHYLCYCLOPHOSPHAMIDE毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RP6159000
- CHEMICAL NAME :
- 2H-1,3,2-Oxazaphosphorine, tetrahydro-2-(bis(2-chloroethyl)amino)-6-trifluoromet hyl-, 2-oxide
- CAS REGISTRY NUMBER :
- 57165-71-6
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C8-H14-Cl2-F3-N2-O2-P
- MOLECULAR WEIGHT :
- 329.11
- WISWESSER LINE NOTATION :
- T6MPOTJ BO BN2G2G DXFFF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 224 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 18,1106,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 18,1106,1975
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标题：57165-71-6_6-TRIFLUOROMETHYLCYCLOPHOSPHAMIDECAS号:57165-71-6_6-TRIFLUOROMETHYLCYCLOPHOSPHAMIDE【结构式 性质 英文】 - 化源网 地址：https://m.chemsrc.com/mip/cas/57165-71-6_1033176.html