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L-α-戊甘氨酸

L-α-戊甘氨酸用途

4-甲基-L-亮氨酸是甘氨酸(HY-Y0966)衍生物[1]。

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L-α-戊甘氨酸名称

[ CAS 号 ]:
57224-50-7

[ 中文名 ]:
L-α-新戊基甘氨酸

[ 英文名 ]:
4-Methyl-L-leucine

[中文别名 ]:

L-Alpha-新戊基甘氨酸

[英文别名 ]:

Glycine, N-(2,2-dimethylpropyl)-
4-Methyl-L-leucine
MFCD00066079
2(S)-amino-4,4-dimethylpentanoic acid
Neopentylglycine
L-Leucine, 4-methyl-
3-tert-Butyl-L-alanine
N-(2,2-Dimethylpropyl)glycine
L-neopentylglycine
4-METHYL-LEUCINE

L-α-戊甘氨酸生物活性

[ 描述 ]:

4-甲基-L-亮氨酸是甘氨酸(HY-Y0966)衍生物[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

氨基酸和氨基酸衍生物已被商业化用作能量补充剂。它们影响合成代谢激素的分泌、运动期间的燃料供应、压力相关任务期间的精神表现,并防止运动引起的肌肉损伤。它们被认为是有益的能生膳食物质[1]。

[参考文献]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

L-α-戊甘氨酸物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
226.1±23.0 °C at 760 mmHg

[ 分子式 ]:
C₇H₁₅NO₂

[ 分子量 ]:
145.199

[ 闪点 ]:
90.6±22.6 °C

[ 精确质量 ]:
145.110275

[ PSA ]:
63.32000

[ LogP ]:
0.97

[ 蒸汽压 ]:
0.0±0.9 mmHg at 25°C

[ 折射率 ]:
1.449

[ 储存条件 ]:
Store at RT.

L-α-戊甘氨酸MSDS

L-α-戊甘氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2922499990

L-α-戊甘氨酸合成路线

L-α-戊甘氨酸上下游产品

L-α-戊甘氨酸上游产品

L-α-戊甘氨酸下游产品

L-α-戊甘氨酸海关

[ 海关编码 ]: 2922499990

[ 中文概述 ]:
2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

L-α-戊甘氨酸文献

The specificity and kinetic mechanism of branched-chain amino acid aminotransferase from Escherichia coli studied with a new improved coupled assay procedure and the enzyme's potential for biocatalysis.

FEBS J. 281(1) , 391-400, (2014)

Branched-chain amino acid aminotransferase (BCAT) plays a key role in the biosynthesis of hydrophobic amino acids (such as leucine, isoleucine and valine), and its substrate spectrum has not been full...

Synthesis of gamma-methyl-L-leucine (neopentylglycine, Neo) and derivatives suitable for peptide synthesis.

Int. J. Pept. Protein Res. 18 , 249, (1981)

The modified Strecker synthesis of Patel & Worsley was combined with an enzymatic deamidation in the final step, to produce the title compound. The amino acid is a member of the family of the "fat" am...

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