R-(+)-氨基谷氨酰胺L-酒石酸盐

R-(+)-氨基谷氨酰胺L-酒石酸盐用途

(R)-Aminoglutethimide tartrate is an anticancer drug that belongs to the family of drugs called nonsteroidal aromatase inhibitors. Aminoglutethimide is used to decrease the production of sex hormones (estrogen in women or testosterone in men) and suppress the growth of tumors that need sex hormones to grow.

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R-(+)-氨基谷氨酰胺L-酒石酸盐名称

[ CAS 号 ]:
57344-88-4

[ 中文名 ]:
R-(+)-氨基谷氨酰胺L-酒石酸盐

[ 英文名 ]:
(R)-Aminoglutethimide tartrate

[英文别名 ]:

d-aminoglutethimide tartrate
R(+)-P-AMINOGLUTETHIMIDE TARTRATE
d-AMinoglutethiMide L-tartrate
R-(+)-Aminoglutethimide L-Tartrate Salt

R-(+)-氨基谷氨酰胺L-酒石酸盐物理化学性质

[ 熔点 ]:
149-150ºC

[ 分子式 ]:
C₁₇H₂₂N₂O₈

[ 分子量 ]:
382.36500

[ 精确质量 ]:
382.13800

[ PSA ]:
187.25000

[ LogP ]:
0.14060

[ 外观性状 ]:
白色固体

R-(+)-氨基谷氨酰胺L-酒石酸盐安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
22-24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

R-(+)-氨基谷氨酰胺L-酒石酸盐文献

Aminoglutethimide medical adrenalectomy for advanced prostatic carcinoma.

J. Urol. 115 , 170-174, (1976)

Complete adrenal suppression with aminoglutethimide has been accomplished in 7 patients with progressive stage D carcinoma of the prostate who had become refractory to orchiectomy and the administrati...

Up-regulation of the endothelin receptor A in placental tissue from first trimester delayed miscarriages.

J. Soc. Gynecol. Investig. 13 , 435-41, (2006)

This study tested the hypothesis that the endothelin (ET)/ET receptor (ETR) system in biologic fluids and in the human placenta is altered in delayed miscarriages as compared to apparently normal earl...

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