1,2,4,7,8-五氯二苯并-对-二恶英

1,2,4,7,8-五氯二苯并-对-二恶英名称

[ CAS 号 ]:
58802-08-7

[ 中文名 ]:
1,2,4,7,8-五氯二苯并-对-二恶英

[ 英文名 ]:
1,2,4,7,8-Pentachlorodibenzo-p-dioxin

[中文别名 ]:

[英文别名 ]:

1,2,4,7,8-五氯二苯并-对-二恶英物理化学性质

[ 密度 ]:
1.714g/cm3

[ 沸点 ]:
443.9ºC at 760mmHg

[ 分子式 ]:
C12H3Cl5O2

[ 分子量 ]:
356.41600

[ 闪点 ]:
171.7ºC

[ 精确质量 ]:
353.85800

[ PSA ]:
18.46000

[ LogP ]:
6.85160

[ 折射率 ]:
1.661

1,2,4,7,8-五氯二苯并-对-二恶英毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HP3420000
CHEMICAL NAME :
Dibenzo-p-dioxin, 1,2,4,7,8-pentachloro-
CAS REGISTRY NUMBER :
58802-08-7
BEILSTEIN REFERENCE NO. :
1627438
LAST UPDATED :
199710
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C12-H3-Cl5-O2
MOLECULAR WEIGHT :
356.40
WISWESSER LINE NOTATION :
T C666 BO IOJ DG EG GG LG MG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 mg/kg
TOXIC EFFECTS :
Endocrine - changes in spleen weight Endocrine - changes in thymus weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 44,335,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
1125 ug/kg
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 44,335,1978 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987
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