1,2,4,7,8-五氯二苯并-对-二恶英
1,2,4,7,8-五氯二苯并-对-二恶英名称
[ CAS 号 ]:
58802-08-7
[ 中文名 ]:
1,2,4,7,8-五氯二苯并-对-二恶英
[ 英文名 ]:
1,2,4,7,8-Pentachlorodibenzo-p-dioxin
[中文别名 ]:
[英文别名 ]:
- Dibenzo-p-dioxin,1,2,4,7,8-pentachloro
- 1,2,4,7,8-P5CDD
- 1,2,4,7,8-pentachlorodibenzodioxin
- 1,2,4,7,8-PCDD
- 1,2,4,7,8-pentachlorooxanthrene
1,2,4,7,8-五氯二苯并-对-二恶英物理化学性质
[ 密度 ]:
1.714g/cm3
[ 沸点 ]:
443.9ºC at 760mmHg
[ 分子式 ]:
C12H3Cl5O2
[ 分子量 ]:
356.41600
[ 闪点 ]:
171.7ºC
[ 精确质量 ]:
353.85800
[ PSA ]:
18.46000
[ LogP ]:
6.85160
[ 折射率 ]:
1.661
1,2,4,7,8-五氯二苯并-对-二恶英毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HP3420000
- CHEMICAL NAME :
- Dibenzo-p-dioxin, 1,2,4,7,8-pentachloro-
- CAS REGISTRY NUMBER :
- 58802-08-7
- BEILSTEIN REFERENCE NO. :
- 1627438
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C12-H3-Cl5-O2
- MOLECULAR WEIGHT :
- 356.40
- WISWESSER LINE NOTATION :
- T C666 BO IOJ DG EG GG LG MG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >5 mg/kg
- TOXIC EFFECTS :
- Endocrine - changes in spleen weight Endocrine - changes in thymus weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 44,335,1978
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 1125 ug/kg
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 44,335,1978 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987
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