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1-(34-二甲氧基苄基)-67-二甲氧基-34-二氢异喹啉盐酸盐

名称

[ CAS 号 ]:
5884-22-0

[ 中文名 ]:
二氢罂粟碱盐酸盐

[ 英文名 ]:
1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-3,4-dihydroisoquinoline hydrochloride

[中文别名 ]:

[英文别名 ]:

DIHYDROALKALI HYDROCHLORIDE
3,4-dihydropapaverine hydrochloride
Dihydropapaverinehydrochloride

物理化学性质

[ 沸点 ]:
482.6ºC at 760mmHg

[ 熔点 ]:
202ºC

[ 分子式 ]:
C₂₀H₂₄ClNO₄

[ 分子量 ]:
377.862

[ 闪点 ]:
196.9ºC

[ 精确质量 ]:
377.139374

[ PSA ]:
49.28000

[ LogP ]:
3.54650

[ 折射率 ]:
1.554

[ 储存条件 ]:
室温

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NW7628980

CHEMICAL NAME :: Isoquinoline, 3,4-dihydro-6,7-dimethoxy-1-veratryl-, hydrochloride

CAS REGISTRY NUMBER :: 5884-22-0

LAST UPDATED :: 198609

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C20-H23-N-O4.Cl-H

MOLECULAR WEIGHT :: 377.90

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: APPBDI Acta Physiologica et Pharmacologica Bulgarica. (Izdatelstvo na Bulgarskata Akademiya na Naukite, ul. Akad. G. Bonchev, 1113 Sofia, Bulgaria) V.1- 1974- Volume(issue)/page/year: 5(3),82,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 5,69,1950

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安全信息

[ 海关编码 ]:
2933499090

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海关

[ 海关编码 ]: 2933499090

[ 中文概述 ]:
2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%