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(S)-(+)-3-哌啶甲酸

(S)-(+)-3-哌啶甲酸用途

Nipecotic acid, S(+)- is a GABA uptake inhibitor.

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(S)-(+)-3-哌啶甲酸名称

[ CAS 号 ]:
59045-82-8

[ 中文名 ]:
(S)-3-哌啶甲酸

[ 英文名 ]:
(S)-(+)-Nipecotic acid

[中文别名 ]:

[英文别名 ]:

hexahydronicotinic acid
(±)-Nipecotic acid
L-Nipecotic acid
(±)-Piperidine-3-carboxylic acid
Nipecotic acid
Piperidine-3-carboxylic acid
(3S)-Piperidine-3-carboxylic acid
3-Piperidinecarboxylic acid
(3S)-3-Piperidinecarboxylic acid
MFCD01630807

(S)-(+)-3-哌啶甲酸物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
265.8±33.0 °C at 760 mmHg

[ 熔点 ]:
254 °C (dec.)

[ 分子式 ]:
C₆H₁₁NO₂

[ 分子量 ]:
129.157

[ 闪点 ]:
114.5±25.4 °C

[ 精确质量 ]:
129.078979

[ PSA ]:
49.33000

[ LogP ]:
-0.04

[ 外观性状 ]:
固体;White powder to crystal

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.479

[ 储存条件 ]:
室温

(S)-(+)-3-哌啶甲酸MSDS

详细MSDS(安全技术说明书)

(S)-(+)-3-哌啶甲酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2933399090

(S)-(+)-3-哌啶甲酸海关

[ 海关编码 ]: 2933399090

[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

(S)-(+)-3-哌啶甲酸文献

Protein prosthesis: β-peptides as reverse-turn surrogates.

Protein Sci. 22(3) , 274-9, (2013)

The introduction of non-natural modules could provide unprecedented control over folding/unfolding behavior, conformational stability, and biological function of proteins. Success requires the interro...

N-methyl phenylalanine-rich peptides as highly versatile blood-brain barrier shuttles.

J. Med. Chem. 53 , 2354-63, (2010)

Here we studied the capacity of N-MePhe-(N-MePhe)(3)-CONH(2), Cha-(N-MePhe)(3)-CONH(2), and 2Nal-(N-MePhe)(3)-CONH(2) to carry various drugs (cargos) in in vitro blood-brain barrier (BBB) models in or...

GABA uptake by purified avian Müller glia cells in culture.

Neurotox. Res. 12(2) , 145-53, (2007)

GABA is the main inhibitory aminoacid transmitter present in neurons and glial cells. Its uptake is carried out by specific high-affinity Na(+)/Cl (-) dependent transporters (GATs). It has been report...

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