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邻甲酚酞

邻甲酚酞用途

【用途一】
酸碱指示剂，变色范围pH8.2（无色）-9.8（红色）。

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邻甲酚酞名称

[ CAS 号 ]:
596-27-0

[ 中文名 ]:
邻甲酚酞

[ 英文名 ]:
o-cresolphthalein

[中文别名 ]:

[英文别名 ]:

3,3'-DIMETHYLPHENOLPHTHALEIN
o-cresolphthalein
MFCD00005912
EINECS 209-881-8

邻甲酚酞物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
555.0±50.0 °C at 760 mmHg

[ 熔点 ]:
223-225 °C

[ 分子式 ]:
C₂₂H₁₈O₄

[ 分子量 ]:
346.376

[ 闪点 ]:
198.8±23.6 °C

[ 精确质量 ]:
346.120514

[ PSA ]:
66.76000

[ LogP ]:
3.55

[ 外观性状 ]:
白色至米色结晶粉末

[ 蒸汽压 ]:
0.0±1.6 mmHg at 25°C

[ 折射率 ]:
1.668

[ 储存条件 ]:
室温

[ 水溶解性 ]:
slightly soluble

邻甲酚酞MSDS

详细MSDS(安全技术说明书)

邻甲酚酞毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SM8390000

CHEMICAL NAME :: Phenolphthalein, 3',3''-dimethyl-

CAS REGISTRY NUMBER :: 596-27-0

BEILSTEIN REFERENCE NO. :: 0310554

LAST UPDATED :: 199709

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C22-H18-O4

MOLECULAR WEIGHT :: 346.40

WISWESSER LINE NOTATION :: T56 BVO DHJ DR DQ C1& DR DQ C1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02167 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1081 No. of Facilities: 127 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 2223 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1081 No. of Facilities: 36 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 903 (estimated) No. of Female Employees: 643 (estimated)

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邻甲酚酞安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R40

[ 安全声明 (欧洲) ]:
S36/37

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
SM8390000

[ 海关编码 ]:
2932209090

邻甲酚酞上下游产品

邻甲酚酞上游产品

邻甲酚酞下游产品

邻甲酚酞制备

1.由苯酐与邻甲苯缩合而得。将苯酐和邻甲酚混合加热熔化，在110℃加入无水氯化锌，并在110-115℃搅拌反应12-18h，通入蒸汽赶出剩余的邻甲酚。将所得粗品氢氧化钠溶液溶解，过滤。滤液用稀盐酸中和，得白色结晶即为成品。

2.将邻甲苯酚与邻苯二甲酸酐混合，在搅拌下慢慢加热至熔化后迅速加入新鲜无水氯化锌，加热至105～110℃，保温5～6h，进行缩合反应：

反应结束后，加入少量水，搅拌使沉淀溶解，然后加到稀盐酸中，待沉淀完全后，过滤，用少量蒸馏水洗涤沉淀数次，将沉淀研碎后再加稀盐酸，过滤。向过滤后的结晶中加入10%的氢氧化钠溶液，搅拌并加热溶解，之后，加入冷蒸馏水，冷却结晶，过滤，用水洗涤结晶至合格。将洗涤液与滤液合并，并加入浓盐酸，冷却结晶，过滤，水洗至合格，并入上述结晶干燥即得邻甲酚酞。

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邻甲酚酞海关

[ 海关编码 ]: 2932209090

[ 中文概述 ]:
2932209090. 其他内酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

邻甲酚酞文献

Hepatorenal protective effect of Antistax(®) against chemically-induced toxicity.

Pharmacogn. Mag. 11 , S173-81, (2015)

Antioxidant natural products and chemoprevention are considered nowadays as an effective approach against health various disorders and diseases induced by oxidative stress or free radicals.The aim of ...

Establishing pediatric reference intervals for 13 biochemical analytes derived from normal subjects in a pediatric endocrinology clinic in Korea.

Clin. Biochem. 47(18) , 268-71, (2014)

Defining pediatric reference intervals is one of the most difficult tasks for laboratory physicians. The continuously changing physiology of growing children makes their laboratory values moving targe...

Relative abundance of fetuin- A in peritoneal dialysis effluent and its association with in situ formation of calciprotein particles: an observational pilot study.

Nephrology (Carlton.) 20(1) , 6-10, (2014)

In patients with renal failure or chronic inflammation, the accumulation of fetuin-A-containing calciprotein particles (CPP) in the extracellular fluid has been implicated in driving inflammatory path...

更多文献

邻甲酚酞

邻甲酚酞用途

邻甲酚酞名称

邻甲酚酞物理化学性质

邻甲酚酞MSDS

详细MSDS(安全技术说明书)

邻甲酚酞毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

邻甲酚酞安全信息

邻甲酚酞上下游产品

邻甲酚酞上游产品

邻甲酚酞下游产品

邻甲酚酞制备

邻甲酚酞海关

邻甲酚酞文献

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