依替前列通

依替前列通名称

[ 英文名 ]:
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-2-[2-(phenoxymethyl)-1,3-dioxolan-2-yl]ethenyl]cyclopentyl]hept-5-enoic acid

[中文别名 ]:

依替前列酮

[英文别名 ]:

Etiprostone [INN-French]
Etiprostonum [INN-Latin]
Etiprostone
Etiprostonum
Etiproston
Etiproston (INN)

依替前列通物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
598.1±50.0 °C at 760 mmHg

[ 分子式 ]:
C₂₄H₃₂O₇

[ 分子量 ]:
432.507

[ 闪点 ]:
200.2±23.6 °C

[ 精确质量 ]:
432.214813

[ PSA ]:
105.45000

[ LogP ]:
1.66

[ 蒸汽压 ]:
0.0±1.8 mmHg at 25°C

[ 折射率 ]:
1.633

依替前列通毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MJ9671000

CHEMICAL NAME :: 5-Heptenoic acid, 7-(3,5-dihydroxy-2-(2-(2-(phenoxymethyl)-1,3-dioxolan -2-yl)ethenyl) cyclopentyl)-, (1R-(1-alpha(Z),2-beta(E),3-alpha,5-alpha))-

CAS REGISTRY NUMBER :: 59619-81-7

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C24-H32-O7

MOLECULAR WEIGHT :: 432.56

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 600 ug/kg

SEX/DURATION :: female 4-7 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - abortion

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 21,443,1978

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

DOSE :: 25 ug/kg

SEX/DURATION :: female 29 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - parturition Reproductive - Effects on Newborn - stillbirth Reproductive - Effects on Newborn - physical

REFERENCE :: ANIPA8 Animal Production. (Scotish Academic Press Ltd., 33 Montgomery Street, Edinburgh EH7 5JX, UK) V.1- 1959- Volume(issue)/page/year: 49,129,1989

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