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5-甲氧基色胺

5-甲氧基色胺用途

用作有机合成中间体

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5-甲氧基色胺名称

[ CAS 号 ]:
608-07-1

[ 中文名 ]:
5-甲氧基色胺

[ 英文名 ]:
5-Methoxy-3-indoleaceate

[中文别名 ]:

[英文别名 ]:

5-Methoxy-3-indoleacetic acid
Mexamine base
(5-Methoxy-1H-indol-3-yl)acetic acid
O-METHYLSEROTONIN
5MOT
5-Methoxyindoleacetic acid
EINECS 200-637-6
5-Methoxytryptamine
indole-3-acetic acid, 5-methoxy-
MFCD00005662

5-甲氧基色胺物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
445.9±30.0 °C at 760 mmHg

[ 熔点 ]:
245-250 °C (dec.)(lit.)

[ 分子式 ]:
C₁₁H₁₄N₂O

[ 分子量 ]:
205.210

[ 闪点 ]:
223.5±24.6 °C

[ 精确质量 ]:
205.073898

[ PSA ]:
51.04000

[ LogP ]:
1.34

[ 外观性状 ]:
白色至黄褐色的结晶粉末

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.656

[ 储存条件 ]:
2-8°C

5-甲氧基色胺MSDS

5-甲氧基色胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NL4059000

CHEMICAL NAME :: Indole, 3-(2-aminoethyl)-5-methoxy-

CAS REGISTRY NUMBER :: 608-07-1

BEILSTEIN REFERENCE NO. :: 0145587

LAST UPDATED :: 199709

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C11-H14-N2-O

MOLECULAR WEIGHT :: 190.27

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 176 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 106 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - excitement Behavioral - muscle contraction or spasticity

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 8 mg/kg

SEX/DURATION :: male 20 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 11 mg/kg

SEX/DURATION :: female 12-22 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - behavioral

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 240 mg/kg

SEX/DURATION :: female 1-2 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 3 gm/kg

REFERENCE :: EKSODD Eksperimental'naya Onkologiya. Experimental Oncology. (V/O Mezhdunarodnaya Kniga, 113095 Mosow, USSR) V.1- 1979- Volume(issue)/page/year: 7(4),26,1985

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5-甲氧基色胺安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 警示性声明 ]:
P301 + P312 + P330

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
NL4110000

[ 海关编码 ]:
2933990090

5-甲氧基色胺合成路线

5-甲氧基色胺上下游产品

5-甲氧基色胺上游产品

5-甲氧基色胺下游产品

5-甲氧基色胺海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

5-甲氧基色胺文献

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