Acetamide,N-(acetyloxy)-N-9H-fluoren-2-yl-
名称
[ CAS 号 ]:
6098-44-8
[ 英文名 ]:
Acetamide,N-(acetyloxy)-N-9H-fluoren-2-yl-
[英文别名 ]:
- N-Acetoxy-2-fluorenylacetamide
- [acetyl(9H-fluoren-2-yl)amino] acetate
- 2-Acetoxyacetylaminofluorene
- 2-acetoxy-2-acetylaminofluorene
- N-Acetoxy-N-2-fluorenylacetamide
- N-Acetoxy-N-acetyl-2-aminofluorene
- N-Acetoxy-2-acetamidofluorene
- ACETOXYACETYLAMINOFLUORENE
- Acetoxyacetamidofluorene
- Acetoxy AAF
物理化学性质
[ 密度 ]:
1.279g/cm3
[ 沸点 ]:
445.1ºC at 760 mmHg
[ 分子式 ]:
C17H15NO3
[ 分子量 ]:
281.30600
[ 闪点 ]:
223ºC
[ 精确质量 ]:
281.10500
[ PSA ]:
46.61000
[ LogP ]:
3.08880
[ 折射率 ]:
1.639
[ 储存条件 ]:
库房通风低温干燥
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NC3420000
- CHEMICAL NAME :
- Hydroxylamine, N,O-diacetyl-N-fluoren-2-yl-
- CAS REGISTRY NUMBER :
- 6098-44-8
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 110
- MOLECULAR FORMULA :
- C17-H15-N-O3
- MOLECULAR WEIGHT :
- 281.33
- WISWESSER LINE NOTATION :
- L B656 HHJ ENV1&OV1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >660 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 21 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 28 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- Specific locus test
- TYPE OF TEST :
- Cytogenetic analysis
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TYPE OF TEST :
- Cytogenetic analysis
- TYPE OF TEST :
- DNA damage
- TYPE OF TEST :
- DNA damage
- TYPE OF TEST :
- Sister chromatid exchange
- TYPE OF TEST :
- DNA adduct
MUTATION DATA
- TYPE OF TEST :
- DNA adduct
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 136 mmol/L
- REFERENCE :
- CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 3,81,1982
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