4,4'-二羟基二苯甲酮
4,4'-二羟基二苯甲酮用途
4,4'-二羟基二苯甲酮名称
[ CAS 号 ]:
611-99-4
[ 中文名 ]:
4,4'-二羟基二苯甲酮
[ 英文名 ]:
4,4'-Dihydroxybenzophenone
[中文别名 ]:
[英文别名 ]:
- 4,4'-dihydoxy-benzophenone
- Methanone, bis(4-hydroxyphenyl)-
- 4,4'-dihydroxy-benzophenone
- 4-hydroxyphenyl ketone
- p,p-dihydroxybenzophenone
- EINECS 210-288-1
- 4,4`-Dihydroxybenzophenone
- DHBP
- 4,4'-DHBP
- 4,4'-bishydroxybenzophenone
4,4'-二羟基二苯甲酮生物活性
4,4'-二羟基二苯甲酮物理化学性质
[ 密度 ]:
1.3±0.1 g/cm3
[ 沸点 ]:
444.8±30.0 °C at 760 mmHg
[ 熔点 ]:
213-215 °C(lit.)
[ 分子式 ]:
C13H10O3
[ 分子量 ]:
214.22
[ 闪点 ]:
237.0±21.1 °C
[ 精确质量 ]:
214.062988
[ PSA ]:
57.53000
[ LogP ]:
2.55
[ 外观性状 ]:
白色至灰白色结晶粉末
[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C
[ 折射率 ]:
1.648
[ 储存条件 ]:
Refrigerator
[ 水溶解性 ]:
insoluble
4,4'-二羟基二苯甲酮MSDS
4,4'-二羟基二苯甲酮毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DJ0880000
- CHEMICAL NAME :
- Benzophenone, 4,4'-dihydroxy-
- CAS REGISTRY NUMBER :
- 611-99-4
- BEILSTEIN REFERENCE NO. :
- 1874572
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C13-H10-O3
- MOLECULAR WEIGHT :
- 214.23
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Micronucleus test
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 200 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 390,21,1997
4,4'-二羟基二苯甲酮安全信息
[ 符号 ]:
GHS07
[ 信号词 ]:
Warning
[ 危害声明 ]:
H315-H317-H319-H335
[ 警示性声明 ]:
P261-P280-P305 + P351 + P338
[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ 危害码 (欧洲) ]:
Xi:Irritant;
[ 风险声明 (欧洲) ]:
R36/37/38
[ 安全声明 (欧洲) ]:
S26-S36/37-S37/39-S36
[ 危险品运输编码 ]:
NONH for all modes of transport
[ WGK德国 ]:
3
[ RTECS号 ]:
DJ0880000
[ 海关编码 ]:
29145000
4,4'-二羟基二苯甲酮合成路线
4,4'-二羟基二苯甲酮上下游产品
4,4'-二羟基二苯甲酮上游产品
4,4'-二羟基二苯甲酮下游产品
4,4'-二羟基二苯甲酮海关
[ 海关编码 ]: 2914501900
[ 中文概述 ]:
2914501900 其他酮酚。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途, 丙酮报明包装
[ Summary ]:
2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
4,4'-二羟基二苯甲酮文献
J. Med. Chem. 48 , 5666-74, (2005)
We investigated the influence of induced fit of the androgen receptor binding pocket on free energies of ligand binding. On the basis of a novel alignment procedure using flexible docking, molecular d...
A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.Bioorg. Med. Chem. Lett. 19 , 4952-7, (2009)
Aggregated amyloid-beta (Abeta) peptide is implicated in the pathology of Alzheimer's disease. In vitro and in vivo, these aggregates are found in a variety of morphologies, including globular oligome...
Small-molecule scaffolds for CYP51 inhibitors identified by high-throughput screening and defined by X-ray crystallography.Antimicrob. Agents Chemother. 51 , 3915-23, (2007)
Sterol 14alpha-demethylase (CYP51), a major checkpoint in membrane sterol biosynthesis, is a key target for fungal antibiotic therapy. We sought small organic molecules for lead candidate CYP51 inhibi...
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¥858.0/500g
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¥489.0/50mg
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¥需询单/1g
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联系人:李先生
产品详情:4,4'-Dihydroxybenzophenone
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区域:上海市浦东新区
价格:
¥179.9/100g
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¥376.9/500g
¥1784.9/3kg
联系人:阿拉丁
产品详情:4,4'-二羟基二苯甲酮
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相关化合物
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