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N,N-二乙基甲酰胺

N,N-二乙基甲酰胺用途

N,N-Diethylformamide is an Industrial solvent claimed to have HIV protease inhibitory action.

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N,N-二乙基甲酰胺名称

[ CAS 号 ]:
617-84-5

[ 中文名 ]:
N,N-二乙基甲酰胺

[ 英文名 ]:
Diethylformamide

[中文别名 ]:

[英文别名 ]:

Diethylformamide
N,N-Diethylformamide
Formamide, N,N-diethyl-
EINECS 210-533-2
MFCD00003287

N,N-二乙基甲酰胺物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
177.5±0.0 °C at 760 mmHg

[ 熔点 ]:
176-177°C

[ 分子式 ]:
C₅H₁₁NO

[ 分子量 ]:
101.147

[ 闪点 ]:
60.6±0.0 °C

[ 精确质量 ]:
101.084061

[ PSA ]:
20.31000

[ LogP ]:
0.05

[ 外观性状 ]:
液体;Colorless to Light yellow to Light orange clear liquid

[ 蒸汽压 ]:
1.0±0.3 mmHg at 25°C

[ 折射率 ]:
1.418

[ 储存条件 ]:
包装完整、轻装轻卸,库房通风、远离明火、高温、与氧化剂、酸分开存放

[ 水溶解性 ]:
水溶性：可溶；可溶于：乙醇,乙醚

N,N-二乙基甲酰胺MSDS

N,N-二乙基甲酰胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LQ1925000

CHEMICAL NAME :: Formamide, N,N-diethyl-

CAS REGISTRY NUMBER :: 617-84-5

BEILSTEIN REFERENCE NO. :: 1209392

LAST UPDATED :: 199709

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C5-H11-N-O

MOLECULAR WEIGHT :: 101.17

WISWESSER LINE NOTATION :: VHN2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1740 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906- Volume(issue)/page/year: 85,72,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1740 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,330,1986

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 26,409,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6943 No. of Facilities: 49 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 6718 (estimated)

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N,N-二乙基甲酰胺安全信息

[ 符号 ]:

GHS02, GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H226-H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36/37/39

[ 危险品运输编码 ]:
UN 1993 3/PG 3

[ WGK德国 ]:
1

[ RTECS号 ]:
LQ1925000

[ 包装等级 ]:
III

[ 危险类别 ]:
3

[ 海关编码 ]:
2924199090

N,N-二乙基甲酰胺合成路线

N,N-二乙基甲酰胺海关

[ 海关编码 ]: 2924199090

[ 中文概述 ]:
2924199090. 其他无环酰胺（包括无环氨基甲酸酯)(包括其衍生物及盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

N,N-二乙基甲酰胺文献

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A new and facile preparation of quinazoline-2,4(1H,3H)-diones was first reported which was the condensation of aromatic o-aminonitriles with DMF or N,N-diethylformamide in the presence of ZnCl(2) (0.5...

Metal-catalyzed reduction of HCONR'2, R' = Me (DMF), Et (DEF), by silanes to produce R'2NMe and disiloxanes: a mechanism unraveled.

J. Am. Chem. Soc. 134(2) , 848-51, (2012)

We demonstrate that using Mo(CO)(6), Mo(CO)(5)NMe(3), and (η(5)-C(5)H(5))Mn(CO)(3) as catalysts for the silane, R(3)SiH, reduction of N,N-dimethylformamide (DMF), and N,N-diethylformamide (DEF), we ca...

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