2-(3-(2-CHLOROETHYL)3-NITROSOUREIDO) ETHYL METHANE SULFONATE

名称

[ CAS 号 ]:
61866-12-4

[ 英文名 ]:
2-(3-(2-CHLOROETHYL)3-NITROSOUREIDO) ETHYL METHANE SULFONATE

[英文别名 ]:

Cnuems
Ethylmethanesulfonato-cnu

物理化学性质

[ 密度 ]:
1.52g/cm3

[ 分子式 ]:
C₆H₁₂ClN₃O₅S

[ 分子量 ]:
273.69500

[ 精确质量 ]:
273.01900

[ PSA ]:
113.52000

[ LogP ]:
1.36610

[ 折射率 ]:
1.554

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: PB1800000

CHEMICAL NAME :: Methanesulfonic acid, 2-(3-(2-chloroethyl)-3-nitrosoureido)ethyl ester

CAS REGISTRY NUMBER :: 61866-12-4

LAST UPDATED :: 198806

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C5-H10-Cl-N3-O5-S

MOLECULAR WEIGHT :: 259.69

WISWESSER LINE NOTATION :: WS1&O1MVNNO&2G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 23 mg/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 13800 ug/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - chronic pulmonary edema Gastrointestinal - ulceration or bleeding from stomach Blood - changes in bone marrow (not otherwise specified)

MUTATION DATA

TYPE OF TEST :: Gene conversion and mitotic recombination

TEST SYSTEM :: Yeast - Saccharomyces cerevisiae

DOSE/DURATION :: 500 umol/L/16H

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 42,45,1977

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安全信息

[ 海关编码 ]:
2924199090

海关

[ 海关编码 ]: 2924199090

[ 中文概述 ]:
2924199090. 其他无环酰胺（包括无环氨基甲酸酯)(包括其衍生物及盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%