依地酸钙钠
依地酸钙钠用途
用作络合剂、临床上用于铅、汞和放射性元素分裂产物的中毒治疗
依地酸钙钠作用
能与多种金属结合成为稳定而可溶的络合物，由尿中排泄，故用于一些金属的中毒，尤其对无机铅中毒效果好（但对四乙基铅中毒无效），对钴、铜、铬、镉、锰及放射性元素（如镭、铀、钍等）均有解毒作用，但对锶无效。本品与汞的络合力不强，很少用于汞中毒的解毒。每日允许摄入量为2.5mg/kg。主要用于治疗铅中毒，亦可治疗镉、锰、铬、镍、钴和铜中毒，以及作诊断用的铅移动试验。
依地酸钙钠名称
[ CAS 号 ]:
62-33-9
[ 中文名 ]:
乙二胺四乙酸二钠钙
[ 英文名 ]:
Disodium monocalcium EDTA
[中文别名 ]:
[英文别名 ]:
- Calcium Disodium Edetate
- edtacal
- Antallin
- Calcium Sodium Edetate
- DISODIUM CALCIUM EDTA
- chelaton
- Calcium sodium EDTA
- Ledclair
- Calcium disodium EDTA
- MFCD00148919
依地酸钙钠物理化学性质
[ 沸点 ]:
614.2ºC at 760 mmHg
[ 分子式 ]:
C10H12CaN2Na2O8
[ 分子量 ]:
374.268
[ 闪点 ]:
325.2ºC
[ 精确质量 ]:
374.001495
[ PSA ]:
167.00000
[ 外观性状 ]:
白色粉末
[ 储存条件 ]:
室温，干燥
[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents.
依地酸钙钠MSDS
依地酸钙钠毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EV7700000
- CHEMICAL NAME :
- Calciate(2-), ((ethylenedinitrilo)tetraacetato)-, disodium
- CAS REGISTRY NUMBER :
- 62-33-9
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 13
- MOLECULAR FORMULA :
- C10-H12-Ca-N2-O8.2Na
- MOLECULAR WEIGHT :
- 374.30
- WISWESSER LINE NOTATION :
- QV1N1VQ2N1VQ1VQ &-CA- &-NA- 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 5,142,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3850 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 117,20,1956
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,188,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 12 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 5,142,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 7 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 5,142,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 6 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,188,1990
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 11,321,1952
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(7),35,1964 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83993 No. of Facilities: 47 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 1203 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83993 No. of Facilities: 236 (estimated) No. of Industries: 6 No. of Occupations: 12 No. of Employees: 24794 (estimated) No. of Female Employees: 14315 (estimated)
依地酸钙钠安全信息
[ 符号 ]:
GHS07
[ 信号词 ]:
Warning
[ 危害声明 ]:
H315-H319-H335
[ 警示性声明 ]:
P261-P305 + P351 + P338
[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves
[ 危害码 (欧洲) ]:
Xi:Irritant;
[ 风险声明 (欧洲) ]:
R36/37/38
[ 安全声明 (欧洲) ]:
S26-S36
[ 危险品运输编码 ]:
NONH for all modes of transport
[ WGK德国 ]:
2
[ RTECS号 ]:
EV7700000
[ 海关编码 ]:
29349990
依地酸钙钠制备
由乙二胺四乙酸与相应量的钙盐和氢氧化钠作用而得。
依地酸钙钠海关
[ 海关编码 ]: 29349990
依地酸钙钠文献
Life Sci. 92(23) , 1110-7, (2013)
The present study was designed for further evaluation of the biochemical mechanism of hepatic mitochondrial dysfunction under oxidative damages induced by organic hydroperoxide, tert-butyl hydroperoxi...
Determination of vanadium in groundwater samples with an improved kinetic spectrophotometric method.Environ. Technol. 35(9-12) , 1165-74, (2014)
A kinetic catalytic method has been developed for the determination of vanadium based on its catalytic effect on the redox reaction of azorubin S and bromate in the presence of a sulphuric and nitric ...
Separation of metals and phosphorus from incinerated sewage sludge ash.Water Sci. Technol. 67(11) , 2488-93, (2013)
Microbial acidification of incinerated sewage sludge ash and dissolution of metals from the acidified ash were investigated using a semi-batch reactor at different solid retention times (SRTs). The av...
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价格：
￥198.0/500g
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产品详情：乙二胺四乙酸二钠钙
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￥549.0/25mg
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产品详情：[Perfemiker]乙二胺四乙酸二钠钙,＞98%
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价格：
￥23.0/1000kg
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相关化合物
【依地酸钙钠】化源网提供依地酸钙钠CAS号62-33-9，依地酸钙钠MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询依地酸钙钠上化源网，专业又轻松。>>电脑版：依地酸钙钠
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