Carbamic acid,(2-chloroethyl)nitroso-, ethyl ester (7CI,8CI,9CI)

名称

[ CAS 号 ]:
6296-45-3

[ 英文名 ]:
Carbamic acid,(2-chloroethyl)nitroso-, ethyl ester (7CI,8CI,9CI)

[英文别名 ]:

物理化学性质

[ 密度 ]:
1.3g/cm3

[ 沸点 ]:
215.4ºC at 760 mmHg

[ 分子式 ]:
C5H9ClN2O3

[ 分子量 ]:
180.59000

[ 闪点 ]:
84.1ºC

[ 精确质量 ]:
180.03000

[ PSA ]:
58.97000

[ LogP ]:
1.36510

[ 折射率 ]:
1.493

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EZ2100000
CHEMICAL NAME :
Carbamic acid, (2-chloroethyl)nitroso-, ethyl ester
CAS REGISTRY NUMBER :
6296-45-3
BEILSTEIN REFERENCE NO. :
1781530
LAST UPDATED :
199612
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C5-H9-Cl-N2-O3
MOLECULAR WEIGHT :
180.61
WISWESSER LINE NOTATION :
ON2OVM2G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes Gastrointestinal - changes in structure or function of esophagus Gastrointestinal - alteration in gastric secretion
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
330 mg/m3/10M
TOXIC EFFECTS :
Behavioral - irritability Lungs, Thorax, or Respiration - other changes
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6500 ug/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - acute pulmonary edema Lungs, Thorax, or Respiration - pleural effusion Skin and Appendages - dermatitis, other (after systemic exposure)
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
75 mg/m3/10M
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
330 mg/m3/10M
TOXIC EFFECTS :
Behavioral - irritability Lungs, Thorax, or Respiration - other changes
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
330 mg/m3/10M
TOXIC EFFECTS :
Behavioral - irritability Lungs, Thorax, or Respiration - other changes
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Rodent - mouse Leukocyte
DOSE/DURATION :
500 nmol/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 43,175,1983
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