N-ethyl-N-(2-methoxyethyl)-4-nitroso-m-toluidine

名称

[ CAS 号 ]:
63134-20-3

[ 英文名 ]:
N-ethyl-N-(2-methoxyethyl)-4-nitroso-m-toluidine

[英文别名 ]:

N-Ethyl-N-(2-methoxyethyl)-4-nitroso-m-toluidine
EINECS 263-915-6

物理化学性质

[ 密度 ]:
1.03g/cm3

[ 沸点 ]:
345.6ºC at 760 mmHg

[ 分子式 ]:
C₁₂H₁₈N₂O₂

[ 分子量 ]:
222.28400

[ 闪点 ]:
162.8ºC

[ 精确质量 ]:
222.13700

[ PSA ]:
41.90000

[ LogP ]:
2.86560

[ 折射率 ]:
1.51

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CY0432100

CHEMICAL NAME :: Benzenamine, N-ethyl-N-(2-methoxyethyl)-3-methyl-4-nitroso-

CAS REGISTRY NUMBER :: 63134-20-3

LAST UPDATED :: 199712

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C12-H18-N2-O2

MOLECULAR WEIGHT :: 222.32

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS 0546491 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Skin and Appendages - hair

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0546491

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0546491

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Kidney, Ureter, Bladder - other changes in urine composition

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0546491

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0546491

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