N-ethyl-N-(2-methoxyethyl)-4-nitroso-m-toluidine

名称

[ CAS 号 ]:
63134-20-3

[ 英文名 ]:
N-ethyl-N-(2-methoxyethyl)-4-nitroso-m-toluidine

[英文别名 ]:

物理化学性质

[ 密度 ]:
1.03g/cm3

[ 沸点 ]:
345.6ºC at 760 mmHg

[ 分子式 ]:
C12H18N2O2

[ 分子量 ]:
222.28400

[ 闪点 ]:
162.8ºC

[ 精确质量 ]:
222.13700

[ PSA ]:
41.90000

[ LogP ]:
2.86560

[ 折射率 ]:
1.51

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CY0432100
CHEMICAL NAME :
Benzenamine, N-ethyl-N-(2-methoxyethyl)-3-methyl-4-nitroso-
CAS REGISTRY NUMBER :
63134-20-3
LAST UPDATED :
199712
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C12-H18-N2-O2
MOLECULAR WEIGHT :
222.32

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS 0546491 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Skin and Appendages - hair
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0546491
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0546491
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Kidney, Ureter, Bladder - other changes in urine composition
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0546491
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0546491
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