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试卤灵

试卤灵用途

Resorufin (NSC 12097) 是一种荧光染料。

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试卤灵名称

[ CAS 号 ]:
635-78-9

[ 中文名 ]:
试卤灵

[ 英文名 ]:
Resorufin

[中文别名 ]:

[英文别名 ]:

7-hydroxy-phenoxazin-3-one
7-Hydroxy-phenoxazin-3-on
7-hydroxyphenoxazin-3-one
Resorufine
3H-Phenoxazin-3-one,7-hydroxy
7-Hydroxy-3H-phenoxazin-3-one
7-Hydroxy-3H-phenoxazine-3-one
MFCD00128991
EINECS 211-241-8
Resorufin

试卤灵生物活性

[ 描述 ]:

Resorufin (NSC 12097) 是一种荧光染料。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Odyniec ML , et al. 'AND'-based fluorescence scaffold for the detection of ROS/RNS and a second analyte. Chem Commun (Camb). 2018 Jul 26;54(61):8466-8469.

试卤灵物理化学性质

[ 密度 ]:
1.46 g/cm3

[ 沸点 ]:
413ºC at 760 mmHg

[ 熔点 ]:
>300 °C(lit.)

[ 分子式 ]:
C₁₂H₇NO₃

[ 分子量 ]:
213.18900

[ 闪点 ]:
203.6ºC

[ 精确质量 ]:
213.04300

[ PSA ]:
63.33000

[ LogP ]:
1.99840

[ 外观性状 ]:
紫色

[ 储存条件 ]:
?20°C

[ 水溶解性 ]:
水溶性：不溶；不溶：乙醚

试卤灵MSDS

详细MSDS(安全技术说明书)

试卤灵毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SP7698000

CHEMICAL NAME :: 3H-Phenoxazin-3-one, 7-hydroxy-

CAS REGISTRY NUMBER :: 635-78-9

BEILSTEIN REFERENCE NO. :: 0174850

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H7-N-O3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,24,1953

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试卤灵安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S37

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
SP7698000

[ 海关编码 ]:
2934999090

试卤灵海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

试卤灵文献

Membrane anchor of cytochrome P450 reductase suppresses the uncoupling of cytochrome P450.

Chem. Pharm. Bull. 63(4) , 286-94, (2015)

Cytochrome P450 reductase (CPR) is an important redox partner of microsomal CYPs. CPR is composed of a membrane anchor and a catalytic domain that contains FAD and flavin mononucleotide (FMN) as redox...

Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors.

ChemMedChem 10(2) , 253-65, (2015)

At present, inhibitors of α/β-hydrolase domain 6 (ABHD6) are viewed as a promising approach to treat inflammation and metabolic disorders. This article describes the development of 1,2,5-thiadiazole c...

Mitochondrial apoptosis-inducing factor is involved in doxorubicin-induced toxicity on H9c2 cardiomyoblasts.

Biochim. Biophys. Acta 1842(12 Pt A) , 2468-78, (2014)

The cardiotoxicity induced by the anti-cancer doxorubicin involves increased oxidative stress, disruption of calcium homeostasis and activation of cardiomyocyte death. Nevertheless, antioxidants and c...

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试卤灵