< 生产厂家价格 >

3,4-亚甲基二氧基甲基苯丙胺

3,4-亚甲基二氧基甲基苯丙胺名称

[ CAS 号 ]:
64057-70-1

[ 中文名 ]:
3,4-亚甲基二氧基甲基苯丙胺

[ 英文名 ]:
s(+)-3 4-mdma hcl

[英文别名 ]:

3,4-亚甲基二氧基甲基苯丙胺物理化学性质

[ 沸点 ]:
100-110ºC at 0.4 mmHg

[ 熔点 ]:
147-148° (Bailey); mp 152-153° (Braun)

[ 分子式 ]:
C₁₁H₁₆ClNO₂

[ 分子量 ]:
229.703

[ 闪点 ]:
11ºC

[ 精确质量 ]:
229.086960

[ PSA ]:
30.49000

[ LogP ]:
2.75860

[ 外观性状 ]:
solid | white

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
H2O: soluble

3,4-亚甲基二氧基甲基苯丙胺MSDS

详细MSDS(安全技术说明书)

3,4-亚甲基二氧基甲基苯丙胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SH5700000

CHEMICAL NAME :: Phenethylamine, N,alpha-dimethyl-3,4-methylenedioxy-, hydrochloride

CAS REGISTRY NUMBER :: 64057-70-1

LAST UPDATED :: 199009

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C11-H15-N-O2.Cl-H

MOLECULAR WEIGHT :: 229.73

WISWESSER LINE NOTATION :: T56 BO DO CHJ G1Y1&M1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 49 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 97 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 14 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Gastrointestinal - nausea or vomiting

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Primate - monkey

DOSE/DURATION :: 22 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 98 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973

点击显示

3,4-亚甲基二氧基甲基苯丙胺安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301-H315-H319-H335

[ 警示性声明 ]:
P261-P301 + P310-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T+

[ 风险声明 (欧洲) ]:
26/27/28-39/23/24/25-23/24/25-11

[ 安全声明 (欧洲) ]:
22-36/37/39-45-36/37-16-7-26

[ 危险品运输编码 ]:
UN 2811 6.1/PG 2

[ WGK德国 ]:
3

[ RTECS号 ]:
SH5700000

3,4-亚甲基二氧基甲基苯丙胺文献

Measuring effects of MDMA (ecstasy) abuse on the rate of cerebral serotonin synthesis.

J. Neurochem. 131(5) , 541-5, (2014)

Brain serotonin synthesis in MDMA (ecstasy) polydrug users: an alpha-[(11) C]methyl-l-tryptophan study.

J. Neurochem. 131(5) , 634-44, (2014)

3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) use may have long-term neurotoxic effects. In this study, positron emission tomography with the tracer alpha-[(11) C]methyl-l-tryptophan ((11) C-AMT) ...

3,4-Methylenedioxy-methamphetamine induces in vivo regional up-regulation of central nicotinic receptors in rats and potentiates the regulatory effects of nicotine on these receptors.

Neurotoxicology 35 , 41-9, (2013)

Nicotine (NIC), the main psychostimulant compound of smoked tobacco, exerts its effects through activation of central nicotinic acetylcholine receptors (nAChR), which become up-regulated after chronic...

更多文献