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1,3-二[三(羟甲基)甲氨基]丙烷

1,3-二[三(羟甲基)甲氨基]丙烷用途

双三丙烷(BTP)是一种水溶性缓冲物质。双三丙烷可用作聚合酶链反应(PCR)的合适缓冲液。双三丙烷可增强限制性内切酶的稳定性或活性[1][2]。

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1,3-二[三(羟甲基)甲氨基]丙烷名称

[ CAS 号 ]:
64431-96-5

[ 中文名 ]:
1,3-双((三羟甲基)甲基氨基)丙烷

[ 英文名 ]:
BIS-TRIS PROPANE

[中文别名 ]:

[英文别名 ]:

BIS-Tris Propane,ULTROL Grade
Bistrishydroxymethylmethylaminopropane
BIS-TRIS PROPANE SIGMAULTRA
BIS-TRISPROPANE,BIOLOGICALBUFFER
BIS-TRIS PROPANE
1,3-Bis[tris(hydroxymethyl)methylamino]propane
MFCD00004689
EINECS 264-899-3

1,3-二[三(羟甲基)甲氨基]丙烷生物活性

[ 描述 ]:

双三丙烷(BTP)是一种水溶性缓冲物质。双三丙烷可用作聚合酶链反应(PCR)的合适缓冲液。双三丙烷可增强限制性内切酶的稳定性或活性[1][2]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. K A Eckert, et al. DNA polymerase fidelity and the polymerase chain reaction. PCR Methods Appl. 1991 Aug;1(1):17-24.

[2]. J R Wenner, et al. Buffer effects on EcoRV kinetics as measured by fluorescent staining and digital imaging of plasmid cleavage. Anal Biochem.

1,3-二[三(羟甲基)甲氨基]丙烷物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
573.3±50.0 °C at 760 mmHg

[ 熔点 ]:
164-165 °C(lit.)

[ 分子式 ]:
C₁₁H₂₆N₂O₆

[ 分子量 ]:
282.334

[ 闪点 ]:
224.5±20.7 °C

[ 精确质量 ]:
282.179077

[ PSA ]:
145.44000

[ LogP ]:
-1.89

[ 外观性状 ]:
白色至灰白色结晶粉末

[ 蒸汽压 ]:
0.0±3.6 mmHg at 25°C

[ 折射率 ]:
1.565

[ 储存条件 ]:
Store at RT.

[ 水溶解性 ]:
H2O: 1 M at 20 °C, clear, colorless

1,3-二[三(羟甲基)甲氨基]丙烷MSDS

详细MSDS(安全技术说明书)

1,3-二[三(羟甲基)甲氨基]丙烷安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R20/21/22;R36/37/38

[ 安全声明 (欧洲) ]:
S22-S24/25-S26

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
29221980

1,3-二[三(羟甲基)甲氨基]丙烷文献

Induction of Neuron-Specific Degradation of Coenzyme A Models Pantothenate Kinase-Associated Neurodegeneration by Reducing Motor Coordination in Mice.

PLoS ONE 10 , e0130013, (2015)

Pantothenate kinase-associated neurodegeneration, PKAN, is an inherited disorder characterized by progressive impairment in motor coordination and caused by mutations in PANK2, a human gene that encod...

Phosphate modulates receptor sulfotyrosine recognition by the chemokine monocyte chemoattractant protein-1 (MCP-1/CCL2).

Org. Biomol. Chem. 13(7) , 2162-9, (2015)

Tyrosine sulfation is a widespread post-translational modification that mediates the interactions of secreted and membrane-associated proteins in such varied biological processes as peptide hormone ac...

Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors.

J. Med. Chem. 58 , 5649-73, (2015)

Overexpression of ATAD2 (ATPase family, AAA domain containing 2) has been linked to disease severity and progression in a wide range of cancers, and is implicated in the regulation of several drivers ...

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