LEDAKRIN
LEDAKRIN名称
[ CAS 号 ]:
6514-85-8
[ 英文名 ]:
LEDAKRIN
LEDAKRIN物理化学性质
[ 密度 ]:
1.269g/cm3
[ 沸点 ]:
522ºC at 760 mmHg
[ 分子式 ]:
C18H21ClN4O2
[ 分子量 ]:
360.83800
[ 闪点 ]:
269.5ºC
[ 精确质量 ]:
360.13500
[ PSA ]:
73.98000
[ LogP ]:
5.05800
LEDAKRIN毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AR9244000
- CHEMICAL NAME :
- Acridine, 9-((3-(dimethylamino)propyl)amino)-1-nitro-, dihydrochloride
- CAS REGISTRY NUMBER :
- 6514-85-8
- LAST UPDATED :
- 199506
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C18-H20-N4-O2.2Cl-H
- MOLECULAR WEIGHT :
- 397.34
- WISWESSER LINE NOTATION :
- T C666 BNJ GNW IM3N1&1 &GH 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 25750 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 725 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 34050 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1010 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Bird - pigeon
- DOSE/DURATION :
- 1010 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - nausea or vomiting
MUTATION DATA
- TYPE OF TEST :
- Host-mediated assay
- TEST SYSTEM :
- Rodent - mouse Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 500 ug/kg
- REFERENCE :
- PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001, 00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year: 31,661,1979
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