左旋盐酸伪麻黄碱
左旋盐酸伪麻黄碱名称
[ CAS 号 ]:
670-40-6
[ 中文名 ]:
左旋盐酸伪麻黄碱
[ 英文名 ]:
(1R,2R)-2-(methylamino)-1-phenylpropan-1-ol,hydrochloride
[英文别名 ]:
- l-Pseudoephedrine hydrochloride
- Pseudoephedrine,hydrochloride,(-)
- EINECS 211-577-5
- (+)-Pseudoephedrine hydrochloride solution
左旋盐酸伪麻黄碱物理化学性质
[ 沸点 ]:
255ºC at 760 mmHg
[ 分子式 ]:
C10H16ClNO
[ 分子量 ]:
201.69300
[ 闪点 ]:
85.6ºC
[ 精确质量 ]:
201.09200
[ PSA ]:
32.26000
[ LogP ]:
2.52080
左旋盐酸伪麻黄碱毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UL5900000
- CHEMICAL NAME :
- Pseudoephedrine, hydrochloride, (-)-
- CAS REGISTRY NUMBER :
- 670-40-6
- LAST UPDATED :
- 199009
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C10-H15-N-O.Cl-H
- MOLECULAR WEIGHT :
- 201.72
- WISWESSER LINE NOTATION :
- QYR&Y1&M1 &GH -L
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 160 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 71,62,1941
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 284 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 158,135,1967
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 80 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 36,363,1929
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