6-O-Acetyl Codeine

6-O-Acetyl Codeine名称

[ CAS 号 ]:
6703-27-1

[ 英文名 ]:
6-O-Acetyl Codeine

[英文别名 ]:

6-O-Acetyl Codeine物理化学性质

[ 密度 ]:
1.3 g/cm3

[ 沸点 ]:
461.2ºC at 760 mmHg

[ 熔点 ]:
132-134ºC

[ 分子式 ]:
C₂₀H₂₃NO₄

[ 分子量 ]:
341.40100

[ 闪点 ]:
232.7ºC

[ 精确质量 ]:
341.16300

[ PSA ]:
48.00000

[ LogP ]:
2.00980

[ 外观性状 ]:
白色晶体

[ 折射率 ]:
1.627

6-O-Acetyl Codeine毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QD0960000

CHEMICAL NAME :: Morphinan-6-alpha-ol, 7,8-didehydro-4,5-alpha-epoxy-3-methoxy-17-methyl-, acetate

CAS REGISTRY NUMBER :: 6703-27-1

LAST UPDATED :: 199106

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H23-N-O4

MOLECULAR WEIGHT :: 341.44

WISWESSER LINE NOTATION :: T B6566 B6/CO 4ABBC R BX HO PN DU GHT&&TTJ FOV1 JO1 P1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 99 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 28ZNAE "Public Health Reports, Supplement." (Washington, DC) Volume(issue)/page/year: 138,10,1938

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6-O-Acetyl Codeine安全信息

[ 符号 ]:

GHS02, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H302 + H312 + H332-H319

[ 警示性声明 ]:
P210-P261-P302 + P352 + P312-P304 + P340 + P312-P337 + P313-P403 + P235

[ 危险品运输编码 ]:
UN 1648 3 / PGII

6-O-Acetyl Codeine合成路线

详细合成路线

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6-O-Acetyl Codeine文献

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Anal. Bioanal. Chem 392(1-2) , 115-27, (2008)

A sensitive and specific method is presented to simultaneously quantify methadone, heroin, cocaine and metabolites in sweat. Drugs were eluted from sweat patches with sodium acetate buffer, followed b...

The detection of acetylcodeine and 6-acetylmorphine in opiate positive urines.

Forensic Sci. Int. 95(1) , 1-10, (1998)

Acetylcodeine (AC), an impurity of illicit heroin synthesis, was investigated as a urinary biomarker for detection of illicit heroin use. One hundred criminal justice urine specimens that had been con...

Detection of non-prescription heroin markers in urine with liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.

J. Anal. Toxicol. 25(6) , 431-8, (2001)

The planned introduction of a prescription heroin program in Germany created a need for differentiation between non-prescription and prescribed diamorphine use. The following substances were chosen as...

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