diethyl-[2-[(2-heptoxyphenyl)carbamoyloxy]propyl]azanium,chloride
名称
[ CAS 号 ]:
68931-03-3
[ 英文名 ]:
diethyl-[2-[(2-heptoxyphenyl)carbamoyloxy]propyl]azanium,chloride
[英文别名 ]:
- carbisocaine chloride
- Carbisocaine hydrochloride
- karbisokaine
- Carbisocaine
- Carbizocaine hydrochloride
- BK-95
物理化学性质
[ 沸点 ]:
434.7ºC at 760 mmHg
[ 分子式 ]:
C21H37ClN2O3
[ 分子量 ]:
400.98300
[ 闪点 ]:
216.7ºC
[ 精确质量 ]:
400.24900
[ PSA ]:
54.29000
[ LogP ]:
6.13020
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FD8940400
- CHEMICAL NAME :
- Carbanilic acid, o-(heptyloxy)-, 2-(diethylamino)-1-methylethyl ester, hydrochloride
- CAS REGISTRY NUMBER :
- 68931-03-3
- LAST UPDATED :
- 199406
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C21-H36-N2-O3.Cl-H
- MOLECULAR WEIGHT :
- 401.05
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 63 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DECRDP Drugs under Experimental and Clinical Research. (Bioscience Ediprint, Blvd. James-Fazy 13, 1201 Geneva 1, Switzerland) V.1- 1977- Volume(issue)/page/year: 12,845,1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 380 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DECRDP Drugs under Experimental and Clinical Research. (Bioscience Ediprint, Blvd. James-Fazy 13, 1201 Geneva 1, Switzerland) V.1- 1977- Volume(issue)/page/year: 12,845,1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 16 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DECRDP Drugs under Experimental and Clinical Research. (Bioscience Ediprint, Blvd. James-Fazy 13, 1201 Geneva 1, Switzerland) V.1- 1977- Volume(issue)/page/year: 12,845,1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 48 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DMDIEQ Drug Metabolism and Drug Interactions. (Freund Publishing House, Suite 500, Chesham House, 150 Regent Street, London, W1R 5FA, United Kingdom) V.6- 1988- Volume(issue)/page/year: 9,321,1991
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CKFRAY Ceskoslovenska Farmacie. (PNS-Ustredni Expedice a Dovoz Tisku, Kafkova 19, 160 00 Prague 6, Czechoslovakia) V.1- 1952- Volume(issue)/page/year: 27,167,1978
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