2-氯乙基乙基硫醚
2-氯乙基乙基硫醚用途
医药中间体
2-氯乙基乙基硫醚名称
[ CAS 号 ]:
693-07-2
[ 中文名 ]:
2-氯乙基乙基硫醚
[ 英文名 ]:
2-Chloroethyl ethyl sulfide
[中文别名 ]:
[英文别名 ]:
- MFCD00000979
- EINECS 211-742-1
- 1-chloro-2-ethylsulfanylethane
2-氯乙基乙基硫醚物理化学性质
[ 密度 ]:
1.07
[ 沸点 ]:
156-157 °C
[ 分子式 ]:
C4H9ClS
[ 分子量 ]:
124.63200
[ 闪点 ]:
52 °C
[ 精确质量 ]:
124.01100
[ PSA ]:
25.30000
[ LogP ]:
1.97830
[ 外观性状 ]:
透明无色至淡黄色液体
[ 折射率 ]:
1.4875-1.4895
[ 储存条件 ]:
库房低温通风干燥,与食品原料分开存放
[ 水溶解性 ]:
不溶
2-氯乙基乙基硫醚MSDS
2-氯乙基乙基硫醚毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WQ3250000
- CHEMICAL NAME :
- Sulfide, chloroethyl ethyl
- CAS REGISTRY NUMBER :
- 693-07-2
- BEILSTEIN REFERENCE NO. :
- 0635672
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C4-H9-Cl-S
- MOLECULAR WEIGHT :
- 124.64
- WISWESSER LINE NOTATION :
- G2S2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 252 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 32 mg/kg/4D-I
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases
MUTATION DATA
- TEST SYSTEM :
- Insect - Drosophila melanogaster
- DOSE/DURATION :
- 5 mmol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 13,19,1971
2-氯乙基乙基硫醚安全信息
[ 符号 ]:
GHS02, GHS05, GHS06, GHS08
[ 信号词 ]:
Danger
[ 危害声明 ]:
H226-H301 + H311 + H331-H314-H350
[ 警示性声明 ]:
P201-P261-P280-P301 + P310-P305 + P351 + P338-P310
[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
Xn:Harmful;
[ 风险声明 (欧洲) ]:
R10;R22;R36/37/38;R40
[ 安全声明 (欧洲) ]:
S36/37/39-S26-S16-S45-S27
[ 危险品运输编码 ]:
1992
[ RTECS号 ]:
WQ3250000
[ 包装等级 ]:
III
[ 危险类别 ]:
3.2
[ 海关编码 ]:
2930909090
2-氯乙基乙基硫醚合成路线
2-氯乙基乙基硫醚上下游产品
2-氯乙基乙基硫醚上游产品
2-氯乙基乙基硫醚下游产品
2-氯乙基乙基硫醚海关
[ 海关编码 ]: 2930909090
[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
2-氯乙基乙基硫醚文献
Anal. Bioanal. Chem 407 , 7037-46, (2015)
Sulfur mustard (HD) adduct to human serum albumin (ALB) at Cys-34 residue has become an important and long-term retrospective biomarker of HD exposure. Here, a novel, sensitive, and convenient approac...
Intratracheal heparin improves plastic bronchitis due to sulfur mustard analog.Pediatr. Pulmonol. 50(2) , 118-26, (2015)
Inhalation of sulfur mustard (SM) and SM analog, 2-chloroethyl ethyl sulfide (CEES), cause fibrinous cast formation that occludes the conducting airways, similar to children with Fontan physiology-ind...
Tissue factor pathway inhibitor prevents airway obstruction, respiratory failure and death due to sulfur mustard analog inhalation.Toxicol. Appl. Pharmacol. 272(1) , 86-95, (2013)
Sulfur mustard (SM) inhalation causes airway injury, with enhanced vascular permeability, coagulation, and airway obstruction. The objective of this study was to determine whether recombinant tissue f...
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