羟乙桂胺
羟乙桂胺名称
[ CAS 号 ]:
6961-46-2
[ 中文名 ]:
羟乙桂胺
[ 英文名 ]:
idrocilamide
[英文别名 ]:
- Brolitene
- N-(2-Hydroxyethyl)cinnamamide
- LCB 29
- Idrocilamidum [INN-Latin]
- Idrocilamide
- Idrocilamida [INN-Spanish]
- N-(Hydroxy-2 ethyl)cinnamamide
- CINNAMAMIDE,N-(2-HYDROXYETHYL)
- Srilane
- N-(Hydroxy-2-aethyl)-cinnamid
羟乙桂胺物理化学性质
[ 密度 ]:
1.146 g/cm3
[ 沸点 ]:
439.4ºC at 760 mmHg
[ 熔点 ]:
100-102°
[ 分子式 ]:
C11H13NO2
[ 分子量 ]:
191.22600
[ 精确质量 ]:
191.09500
[ PSA ]:
49.33000
[ LogP ]:
1.19920
羟乙桂胺毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GD7360000
- CHEMICAL NAME :
- Cinnamamide, N-(2-hydroxyethyl)-
- CAS REGISTRY NUMBER :
- 6961-46-2
- LAST UPDATED :
- 199201
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C11-H13-N-O2
- MOLECULAR WEIGHT :
- 191.25
- WISWESSER LINE NOTATION :
- Q2MV1U1R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >3 gm/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Behavioral - irritability
- REFERENCE :
- EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 9,205,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 28,28,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2950 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness Behavioral - irritability
- REFERENCE :
- EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 9,205,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >150 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Behavioral - irritability
- REFERENCE :
- EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 9,205,1974
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