他洛普仑

他洛普仑用途

Talopram hydrochloride is a the HCl salt of Talopram -- a selective norepinephrine reuptake inhibitor (NRI). Along with talsupram, talopram is structurally related to the selective serotonin reuptake inhibitor (SSRI) citalopram, as well as to melitracen.

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他洛普仑名称

[ CAS 号 ]:
7013-41-4

[ 中文名 ]:
他洛普仑

[ 英文名 ]:
Talopram hydrochloride

[英文别名 ]:

Efaroxan hydrochloride
Talopram

他洛普仑物理化学性质

[ 沸点 ]:
65.43ºC at 760 mmHg

[ 分子式 ]:
C₂₀H₂₅NO

[ 分子量 ]:
295.41900

[ 闪点 ]:
403.1ºC

[ 精确质量 ]:
295.19400

[ PSA ]:
21.26000

[ LogP ]:
4.58600

他洛普仑毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TH8837500

CHEMICAL NAME :: 1-Phthalanpropylamine, 1-phenyl-N,3,3-trimethyl-, hydrochloride

CAS REGISTRY NUMBER :: 7013-41-4

LAST UPDATED :: 199012

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H25-N-O.Cl-H

MOLECULAR WEIGHT :: 331.92

WISWESSER LINE NOTATION :: T56 COT&J B3M1 BR& D1 D1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 71 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 24,121,1966