1,4-BIS((2-((2-HYDROXYETHYL)AMINO)ETHYL) AMINO)-9,10-ANTHRACENEDIONE DIACETATE

名称

[ CAS 号 ]:
70711-40-9

[ 英文名 ]:
1,4-BIS((2-((2-HYDROXYETHYL)AMINO)ETHYL) AMINO)-9,10-ANTHRACENEDIONE DIACETATE

[英文别名 ]:

Ametantrone acetate (usan)
Ametantrone acetate

物理化学性质

[ 沸点 ]:
708.8ºC at 760mmHg

[ 分子式 ]:
C₂₄H₃₂N₄O₆

[ 分子量 ]:
472.53400

[ 闪点 ]:
382.4ºC

[ 精确质量 ]:
472.23200

[ PSA ]:
160.02000

[ LogP ]:
1.46830

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开存放

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CB5748300

CHEMICAL NAME :: Anthraquinone, 1,4-bis((2-((2-hydroxyethyl)amino)ethyl)amino)-, diacetate

CAS REGISTRY NUMBER :: 70711-40-9

LAST UPDATED :: 198910

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C22-H28-N4-O4.2C2-H4-O2

MOLECULAR WEIGHT :: 532.66

WISWESSER LINE NOTATION :: T C666 BV IVJ DM2M2Q GM2M2Q &QV1 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 495 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 62830 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 297 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 34 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 21650 ug/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 5200 ug/kg

SEX/DURATION :: female 6-18 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - other developmental abnormalities

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 10 nmol/L

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 39,2574,1979

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