Aptazapine

Aptazapine名称

[ CAS 号 ]:
71576-41-5

[ 英文名 ]:
Aptazapine

[英文别名 ]:

Aptazapine物理化学性质

[ 分子式 ]:
C20H23N3O4

[ 分子量 ]:
369.41400

[ 精确质量 ]:
369.16900

[ PSA ]:
86.01000

[ LogP ]:
2.05760

Aptazapine毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ4730325
CAS REGISTRY NUMBER :
71576-41-5
LAST UPDATED :
199512
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C16-H19-N3.C4-H4-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
43680 mg/kg/2Y-I
TOXIC EFFECTS :
Cardiac - other changes Endocrine - other changes Kidney, Ureter, Bladder - other changes
REFERENCE :
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 6,46,1986
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
32760 mg/kg/78W-I
TOXIC EFFECTS :
Cardiac - other changes Liver - other changes Kidney, Ureter, Bladder - other changes
REFERENCE :
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 6,46,1986
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
1092 mg/kg/52W-I
TOXIC EFFECTS :
Brain and Coverings - other degenerative changes Liver - other changes Kidney, Ureter, Bladder - other changes
REFERENCE :
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 6,46,1986
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