1-nitro-2-nitroso-1-propylguanidine
1-nitro-2-nitroso-1-propylguanidine名称
[ CAS 号 ]:
71598-10-2
[ 英文名 ]:
1-nitro-2-nitroso-1-propylguanidine
[英文别名 ]:
- PNNG
- GUANIDINE,1-NITRO-3-NITROSO-1-PROPYL
- 3-Nitroso-1-nitro-1-propylguanidine
1-nitro-2-nitroso-1-propylguanidine物理化学性质
[ 密度 ]:
1.514g/cm3
[ 沸点 ]:
295.815ºC at 760 mmHg
[ 分子式 ]:
C4H9N5O3
[ 分子量 ]:
175.14600
[ 闪点 ]:
132.704ºC
[ 精确质量 ]:
175.07100
[ PSA ]:
117.86000
[ LogP ]:
1.28920
[ 折射率 ]:
1.594
1-nitro-2-nitroso-1-propylguanidine毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MF4640000
- CHEMICAL NAME :
- Guanidine, 1-nitro-3-nitroso-1-propyl-
- CAS REGISTRY NUMBER :
- 71598-10-2
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 14
- MOLECULAR FORMULA :
- C4-H9-N5-O3
- MOLECULAR WEIGHT :
- 175.18
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2172 mg/kg/52W-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 60 mg/kg/5W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2172 mg/kg/52W-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3080 mg/kg/44W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3665 mg/kg/44W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
- TYPE OF TEST :
- DNA damage
- TYPE OF TEST :
- Unscheduled DNA synthesis
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 10 mg/L
- REFERENCE :
- GMCRDC Gann Monograph on Cancer Research. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No. 11- 1971- Volume(issue)/page/year: 27,95,1981
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