(Diacetyl)-α-MSH trifluoroacetate salt

用途

(二乙酰基)-α-MSH是一种肽化合物,它在α-MSH分子中引入一个草酰基(二乙酰),可以增加多肽的生物活性[1]。
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名称

[ CAS 号 ]:
71952-90-4

[ 英文名 ]:
(Diacetyl)-α-MSH trifluoroacetate salt

[英文别名 ]:

生物活性

[ 描述 ]:

(二乙酰基)-α-MSH是一种肽化合物,它在α-MSH分子中引入一个草酰基(二乙酰),可以增加多肽的生物活性[1]。

[ 相关类别 ]:

研究领域 >> 其他
信号通路 >> 其他 >> 其他

[参考文献]

[1]. R J Arends, et al. alpha-MSH acetylation in the pituitary gland of the sea bream (Sparus aurata L.) in response to different backgrounds, confinement and air exposure. J Endocrinol. 2000 Aug;166(2):427-35.  

物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 分子式 ]:
C79H111N21O20S

[ 分子量 ]:
1706.92

[ 精确质量 ]:
1705.803467

[ PSA ]:
674.35000

[ LogP ]:
-0.61

[ 外观性状 ]:
白色粉末

[ 折射率 ]:
1.674

安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

文献

A role for di-acetyl alpha-melanocyte-stimulating hormone in the control of cortisol release in the teleost Oreochromis mossambicus.

J. Endocrinol. 135(2) , 285-92, (1992)

In stressed tilapia, Oreochromis mossambicus, total alpha-melanocyte-stimulating hormone (alpha-MSH) levels and di-acetyl alpha-MSH/mono-acetyl alpha-MSH (di:mono) ratios are elevated. We therefore in...

Bromocriptine-induced changes in the biochemistry, physiology, and histology of the intermediate lobe of the rat pituitary gland.

Endocrinology 114(5) , 1871-84, (1984)

Treatment of rats with 2-Br-alpha-ergocryptine (bromocriptine; CB 154) elicits biochemical, physiological, and histological changes in the intermediate lobe (IL) of the rat pituitary gland, suggesting...

alpha-Melanocyte-stimulating hormone-like peptides in the intermediate lobe of the rat pituitary gland: characterization of content and release in vitro.

Endocrinology 112(2) , 435-41, (1983)

Reverse phase high performance liquid chromatography (HPLC) followed by RIA of the chromatographic fractions was used to separate and quantify, respectively, the alpha MSH-like peptides stored in the ...


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相关化合物

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