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环庚米特

环庚米特用途

Cyheptamide is an anticonvulsant.

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环庚米特名称

[ CAS 号 ]:
7199-29-3

[ 中文名 ]:
环庚米特

[ 英文名 ]:
Cyheptamide

[中文别名 ]:

[英文别名 ]:

Cyheptamine
BS 7029
AY 8682
EINECS 230-570-8
CYHEPTAMIDE
Dibenzo<a,d>1,4-cycloheptadien-5-carboxamid

环庚米特物理化学性质

[ 密度 ]:
1.173 g/cm3

[ 沸点 ]:
438.8ºC at 760 mmHg

[ 熔点 ]:
193-194ºC

[ 分子式 ]:
C₁₆H₁₅NO

[ 分子量 ]:
237.29600

[ 闪点 ]:
219.2ºC

[ 精确质量 ]:
237.11500

[ PSA ]:
43.09000

[ LogP ]:
3.10270

[ 折射率 ]:
1.62

环庚米特MSDS

环庚米特毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HO7878000

CHEMICAL NAME :: 5H-Dibenzo(a,d)cycloheptene-5-carboxamide, 10,11-dihydro-

CAS REGISTRY NUMBER :: 7199-29-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C16-H15-N-O

MOLECULAR WEIGHT :: 237.32

WISWESSER LINE NOTATION :: L C676&T&J BVZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,68,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,68,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1830 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,68,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 630 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 7,88,1964

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环庚米特安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
HO7878000

[ 海关编码 ]:
2924299090

环庚米特合成路线

环庚米特海关

[ 海关编码 ]: 2924299090

[ 中文概述 ]:
2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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J. Pharm. Sci. 103(8) , 2520-9, (2014)

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Cyheptamide and 3-hydroxy-3-phenacyloxindole: structural similarity to diphenylhydantoin as the basis for anticonvulsant activity.

J. Med. Chem. 27(5) , 649-54, (1984)

The molecular structures of cyheptamide and 3-hydroxy-3- phenacyloxindole were determined by X-ray diffraction methods. The amide group in both compounds exhibits delocalization of the pi-electrons ov...

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